European Journal of Internal Medicine
Volume 16, Issue 8 , Pages 551-560 , December 2005

Disseminated intravascular coagulopathy in aortic aneurysms

  • A. Fernandez-Bustamante

      Affiliations

    • Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University, Baltimore, Maryland, USA
    • ,
  • A. Jimeno

      Affiliations

    • Department of Oncology, Johns Hopkins University, Baltimore, Maryland, USA
    • Corresponding Author InformationCorresponding author. The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, 1650 Orleans St. Room 162 A, Baltimore, Maryland 21231 U.S.A. Tel.: +1 410 5025835; fax: +1 410 6149006.

Received 10 February 2005 ,Revised 10 May 2005 ,Accepted 2 June 2005.

References 

  1. Fine NL, Applebaum J, Elguezabal A, Castleman L. Multiple coagulation defects in association with dissecting aneurysm. Arch Intern Med. 1967;119:522–526
  2. Bick RL. Disseminated intravascular coagulation current concepts of etiology, pathophysiology, diagnosis, and treatment. Hematol Oncol Clin North Am. 2003;17:149–176
  3. Taylor FB, Toh CH, Hoots WK, Wada H, Levi M. Towards definition, clinical and laboratory criteria, and a scoring system for disseminated intravascular coagulation. Thromb Haemost. 2001;86:1327–1330
  4. Bakhtiari K, Meijers JC, de Jonge E, Levi M. Prospective validation of the International Society of Thrombosis and Haemostasis scoring system for disseminated intravascular coagulation. Crit Care Med. 2004;32:2416–2421
  5. Wada H, Gabazza EC, Asakura H, Koike K, Okamoto K, Maruyama I, et al. Comparison of diagnostic criteria for disseminated intravascular coagulation (DIC): diagnostic criteria of the International Society of Thrombosis and Hemostasis and of the Japanese Ministry of Health and Welfare for overt DIC. Am J Hematol. 2003;74:17–22
  6. Toh CH, Downey C. Performance and prognostic importance of a new clinical and laboratory scoring system for identifying non-overt disseminated intravascular coagulation. Blood Coagul Fibrinolysis. 2005;16:69–74
  7. Fuster, V, Hurst, JW, Hurst's the heart. 11th ed. New York, London: McGraw-Hill Professional, McGraw-Hill; 2004.
  8. Kasper DL, Harrison TR. Harrison's principles of internal medicine. 16th/ed.. New York: McGraw-Hill Medical Pub. Division; 2005;
  9. Mulcare RJ, Royster TS, Phillips LL. Intravascular coagulation in surgical procedures on the abdominal aorta. Surg Gynecol Obstet. 1976;143:730–734
  10. Keagy BA, Pharr WF, Bowes DE. Unusual presentations of abdominal aortic aneurysms. J Cardiovasc Surg (Torino). 1981;22:41–46
  11. Fisher DF, Yawn DH, Crawford ES. Preoperative disseminated intravascular coagulation associated with aortic aneurysms. A prospective study of 76 cases. Arch Surg. 1983;118:1252–1255
  12. Mukaiyama H, Shionoya S, Ikezawa T, Kamiya T, Hamaguchi M, Saito H. Abdominal aortic aneurysm complicated with chronic disseminated intravascular coagulopathy: a case of surgical treatment. J Vasc Surg. 1987;6:600–604
  13. Thompson RW, Adams DH, Cohen JR, Mannick JA, Whittemore AD. Disseminated intravascular coagulation caused by abdominal aortic aneurysm. J Vasc Surg. 1986;4:184–186
  14. Miyata T, Tada Y, Takagi A, Oshima A, Shirakawa M, Idezuki Y. Disseminated intravascular coagulation caused by abdominal aortic aneurysm. J Cardiovasc Surg (Torino). 1988;29:494–497
  15. Mamiya S, Endo Y, Miura AB, Kanazawa T, Kuwayama A, Nishimura S. Disseminated intravascular coagulation accompanying thoracic and abdominal aortic aneurysm; report of three cases. Jpn J Med. 1988;27:91–95
  16. Oba J, Shiiya N, Matsui Y, Goda T, Sakuma M, Yasuda K. Preoperative disseminated intravascular coagulation (DIC) associated with aortic aneurysm—does it need to be corrected before surgery?. Surg Today. 1995;25:1011–1014
  17. Aboulafia DM, Aboulafia ED. Aortic aneurysm-induced disseminated intravascular coagulation. Ann Vasc Surg. 1996;10:396–405
  18. Adam DJ, Haggart PC, Ludlam CA, Bradbury AW. Hemostatic markers before operation in patients with acutely symptomatic nonruptured and ruptured infrarenal abdominal aortic aneurysm. J Vasc Surg. 2002;35:661–665
  19. Majumdar G. Long-term management of chronic DIC associated with inoperable aortic aneurysm with low molecular weight heparin. Hematol J. 2004;5:447–448
  20. Jelenska MM. Coagulation parameters as predictors of DIC in patients with intact aortic aneurysm. Hamostaseologie. 2004;24:162–166
  21. Siebert WT, Natelson EA. Chronic consumption coagulopathy accompanying abdominal aortic aneurysm. Arch Surg. 1976;111:539–541
  22. Prentice CR, McNicol GP, Douglas AS. Effects on blood coagulation, fibrinolysis, and platelet aggregation of normal and atheronatous aortic tissue. J Clin Pathol. 1966;19:154–158
  23. Straub PW, Kessler S. Metabolism and localization of I 131-fibrinogen in chronic intravascular coagulation. Schweiz Med Wochenschr. 1970;100:2001–2003
  24. ten Cate JW, Timmers H, Becker AE. Coagulopathy in ruptured or dissecting aortic aneurysms. Am J Med. 1975;59:171–176
  25. Haithcock BE, Shepard AD, Raman SBK, Conrad MF, Pandurangi K, Fanous NH. Activation of fibrinolytic pathways is associated with duration of supraceliac aortic cross-clamping*1. J Vasc Surg. 2004;40:325–333
  26. Hellstern P, Haubelt H. Indications for plasma in massive transfusion. Thromb Res. 2002;107(Suppl 1):S19–S22
  27. Levi M, de Jonge E, van der Poll T. Therapeutic intervention in disseminated intravascular coagulation: have we made any progress in the last millennium?. Blood Rev. 2002;16(Suppl 1):S29–S34
  28. Levi M, de Jonge E, van der Poll T. New treatment strategies for disseminated intravascular coagulation based on current understanding of the pathophysiology. Ann Med. 2004;36:41–49
  29. Hoots WK. Non-overt disseminated intravascular coagulation: definition and pathophysiological implications. Blood Rev. 2002;16(Suppl 1):S3–S9
  30. Slofstra SH, Spek CA, ten Cate H. Disseminated intravascular coagulation. Hematol J. 2003;4:295–302
  31. Krevans JR, Jackson DP, Conley CL, Hartmann RC. The nature of the hemorrhagic disorder accompanying hemolytic transfusion reactions in man. Blood. 1957;12:834–843
  32. Langdell RD, Hedgpeth EM. A study of the role of hemolysis in the hemostatic defect of transfusion reactions. Thromb Diath Haemorrh. 1959;3:566–571
  33. Gross SJ, Filston HC, Anderson JC. Controlled study of treatment for disseminated intravascular coagulation in the neonate. J Pediatr. 1982;100:445–448
  34. Toh CH, Dennis M. Current clinical practice. DIC 2002: a review of disseminated intravascular coagulation. Hematology. 2003;8:65–71
  35. Mueller MM, Bomke B, Seifried E. Fresh frozen plasma in patients with disseminated intravascular coagulation or in patients with liver diseases. Thromb Res. 2002;107(Suppl 1):S9–S17
  36. Practice guidelines for blood component therapy: a report by the American society of anesthesiologists task force on blood component therapy. Anesthesiology. 1996;84:732–747
  37. Contreras M, Ala FA, Greaves M, Jones J, Levin M, Machin SJ, et al. Guidelines for the use of fresh frozen plasma. British Committee for Standards in Haematology, Working Party of the Blood Transfusion Task Force. Transfus Med. 1992;2:57–63
  38. Hellstern P, Muntean W, Schramm W, Seifried E, Solheim BG. Practical guidelines for the clinical use of plasma. Thromb Res. 2002;107(Suppl 1):S53–S57
  39. Rohrer MJ, Natale AM. Effect of hypothermia on the coagulation cascade. Crit Care Med. 1992;20:1402–1405
  40. Hiippala ST. Dextran and hydroxyethyl starch interfere with fibrinogen assays. Blood Coagul Fibrinolysis. 1995;6:743–746
  41. Kanda T, Kaneko K, Yamauchi Y, Kanazawa N, Sasaki T, Takeuchi H. Indium 111-labeled platelets accumulation over abdominal aortic graft with chronic disseminated intravascular coagulation—a case history. Angiology. 1993;44:420–424
  42. Micallef-Eynaud PD, Ludlam CA. Aortic aneurysms and consumptive coagulopathy. Blood Coagul Fibrinolysis. 1991;2:477–481
  43. Dorffler-Melly J, de Jonge E, Pont AC, Meijers J, Vroom MB, Buller HR, et al. Bioavailability of subcutaneous low-molecular-weight heparin to patients on vasopressors. Lancet. 2002;359:849–850
  44. Taylor FB, Chang A, Esmon CT, D'Angelo A, Vigano-D'Angelo S, Blick KE. Protein C prevents the coagulopathic and lethal effects of Escherichia coli infusion in the baboon. J Clin Invest. 1987;79:918–925
  45. Bernard GR, Vincent JL, Laterre PF, LaRosa SP, Dhainaut JF, Lopez-Rodriguez A, et al. Efficacy and safety of recombinant human activated protein C for severe sepsis. N Engl J Med. 2001;344:699–709
  46. Bernard GR. Drotrecogin alfa (activated) (recombinant human activated protein C) for the treatment of severe sepsis. Crit Care Med. 2003;31:S85–S93
  47. Vincent JL, Angus DC, Artigas A, Kalil A, Basson BR, Jamal HH, et al. Effects of drotrecogin alfa (activated) on organ dysfunction in the PROWESS trial. Crit Care Med. 2003;31:834–840
  48. Levi M, de Jonge E, van der Poll T, ten Cate H. Disseminated intravascular coagulation. Thromb Haemost. 1999;82:695–705
  49. Warren BL, Eid A, Singer P, Pillay SS, Carl P, Novak I, et al. Caring for the critically ill patient. High-dose antithrombin III in severe sepsis: a randomized controlled trial. Jama. 2001;286:1869–1878
  50. Abraham E, Reinhart K, Svoboda P, Seibert A, Olthoff D, Dal Nogare A, et al. Assessment of the safety of recombinant tissue factor pathway inhibitor in patients with severe sepsis: a multicenter, randomized, placebo-controlled, single-blind, dose escalation study. Crit Care Med. 2001;29:2081–2089
  51. Abraham E, Reinhart K, Opal S, Demeyer I, Doig C, Rodriguez AL, et al. Efficacy and safety of tifacogin (recombinant tissue factor pathway inhibitor) in severe sepsis: a randomized controlled trial. JAMA. 2003;290:238–247
  52. Utoh J, Goto H, Hirata T, Kunitomo R, Hara M, Kitamura N. Anticoagulant effects of argatroban on the pre-DIC state in patients with an aortic aneurysm: a comparative study of heparin. Int J Angiol. 1998;7:231–233
  53. Takada A, Takada Y, Mori T, Sakaguchi S. Prevention of severe bleeding by tranexamic acid in a patient with disseminated intravascular coagulation. Thromb Res. 1990;58:101–108
  54. Takada A, Takada Y. Inhibition by tranexamic acid of the conversion of single-chain tissue plasminogen activator to its two chain form by plasmin: the presence on tissue plasminogen activator of a site to bind with lysine binding sites of plasmin. Thromb Res. 1989;55:717–725
  55. Schnetzer GW, Penner JA. Chronic intravascular coagulation syndrome associated with atherosclerotic aortic aneurysm. South Med J. 1973;66:264–268
  56. Bruzgo I, Tomasiak M, Stelmach H, Midura-Nowaczek K. The effect of some epsilon-aminocaproic acid derivatives on platelet responses. Acta Biochim Pol. 2004;51:73–80
  57. Adam DJ, Haggart PC, Ludlam CA, Bradbury AW. Coagulopathy and hyperfibrinolysis in ruptured abdominal aortic aneurysm repair. Ann Vasc Surg. 2004;18:572–577
  58. Bick RL. Hemostasis defects associated with cardiac surgery, prosthetic devices, and other extracorporeal circuits. Semin Thromb Hemost. 1985;11:249–280
  59. Kamineni R, Heuser RR. Abdominal aortic aneurysm: a review of endoluminal treatment. Null. 2004;17:437–445
  60. Carroccio A, Ellozy SH, Marin ML, Hollier LH. Ten years' experience treating abdominal aortic aneurysms with stent-grafts. Adv Surg. 2004;38:267–280
  61. Sakamoto I, Matsuyama N, Fukushima A, Hayashi H, Nishida A, Hazama S, et al. Chronic aortic dissection complicated by disseminated intravascular coagulation: successful treatment with endovascular stent-grafting. J Endovasc Ther. 2003;10:953–957
  62. Jimeno A, Toledo T, Moya I, Gonzalez-Barber A. Chronic disseminated intravascular coagulation caused by an aorto-bifemoral aneurysm. Eur J Intern Med. 2005;16:298–300

PII: S0953-6205(05)00292-X

doi: 10.1016/j.ejim.2005.06.015

European Journal of Internal Medicine
Volume 16, Issue 8 , Pages 551-560 , December 2005

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