European Journal of Internal Medicine
Volume 17, Issue 7 , Pages 500-502 , November 2006

Antiphospholipid syndrome mimicking multiple sclerosis in two patients

  • Francisco J. Fernández-Fernández

      Affiliations

    • Servicio de Medicina Interna, Complexo Hospitalario Universitario de Vigo, R/ Pizarro 22, 36204 Vigo (Pontevedra), Spain
    • Corresponding Author InformationCorresponding author. Servicio de Medicina Interna, Hospital POVISA, C/ Salamanca 5, 36211 Vigo (Pontevedra), Spain. Tel.: +34 986 413 144; fax: +34 986 421 439.
    • ,
  • Alberto Rivera-Gallego

      Affiliations

    • Servicio de Medicina Interna, Complexo Hospitalario Universitario de Vigo, R/ Pizarro 22, 36204 Vigo (Pontevedra), Spain
    • ,
  • Javier de la Fuente-Aguado

      Affiliations

    • Servicio de Medicina Interna, Complexo Hospitalario Universitario de Vigo, R/ Pizarro 22, 36204 Vigo (Pontevedra), Spain
    • ,
  • Silvia Pérez-Fernández

      Affiliations

    • Servicio de Medicina Interna, Complexo Hospitalario Universitario de Vigo, R/ Pizarro 22, 36204 Vigo (Pontevedra), Spain
    • ,
  • Delicias Muñoz-Fernández

      Affiliations

    • Servicio de Neurología, Complexo Hospitalario Universitario de Vigo, R/ Pizarro 22, 36204 Vigo (Pontevedra), Spain

Received 14 November 2005 ,Revised 10 February 2006 ,Accepted 20 February 2006.

References 

  1. Scott TF, Hess D, Brillman J. Antiphospholipid antibody syndrome mimicking multiple sclerosis clinically and by magnetic resonance imaging. Arch Intern Med. 1994;154:917–920
  2. Siam AM, Hammoudeh M, Khanjar I. Multiple sclerosis-like picture in association with Hughes syndrome. Lupus. 1998;7:367–369
  3. Ijdo JW, Conti-Kelly AM, Greco P, Abedi M, Amos M, Provenzale JM, et al. Anti-phospholipid antibodies in patients with multiple sclerosis and MS-like illnesses: MS or APS?. Lupus. 1999;8:109–115
  4. Cuadrado MJ, Khamashta MA, Ballesteros A, Godfrey T, Simon MJ, Hughes GRV. Can neurologic manifestations of Hughes (Antiphospholipid) syndrome be distinguished from multiple sclerosis? Analysis of 27 patients and review of the literature. Medicine (Baltimore). 2000;79:57–68
  5. Karussis D, Leker RR, Ashkenazi A, Abramsky O. A subgroup of multiple sclerosis patients with anticardiolipin antibodies and unusual clinical manifestations: do they represent a new nosological entity?. Ann Neurol. 1998;44:629–634
  6. Sastre-Garriga J, Reverter JC, Font J, Tintoré M, Espinosa G, Montalban X. Anticardiolipin antibodies are not a useful screening tool in a nonselected large group of patients with multiple sclerosis. Ann Neurol. 2001;49:408–411

PII: S0953-6205(06)00125-7

doi: 10.1016/j.ejim.2006.02.018

European Journal of Internal Medicine
Volume 17, Issue 7 , Pages 500-502 , November 2006

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