European Journal of Internal Medicine
Volume 18, Issue 3 , Pages 202-208 , May 2007

Oral anticoagulation in atrial fibrillation: A pan-European patient survey

  • G.Y.H. Lip

      Affiliations

    • Haemostasis, Thrombosis & Vascular Biology Unit, University Department of Medicine, City Hospital, Birmingham, B18 7QH, UK
    • Corresponding Author InformationCorrespondence author. Tel.: +44 121 507 5080; fax: +44 121 554 4083.
    • ,
  • G. Agnelli

      Affiliations

    • Division of Internal and Cardiovascular Medicine, Department of Internal Medicine, University of Perugia, Perugia, Italy
    • ,
  • A.A. Thach

      Affiliations

    • IPSOS Health, Harrow, UK
    • ,
  • E. Knight

      Affiliations

    • Anticoagulation Europe, Bromley, UK
    • ,
  • D. Rost

      Affiliations

    • Christiansfeld, Denmark
    • ,
  • M.J.D. Tangelder

      Affiliations

    • AstraZeneca R&D, Clinical Science, Mölndal, Sweden

Received 7 April 2006 ,Revised 1 September 2006 ,Accepted 2 November 2006.

References 

  1. Wolf PA, Abbott RD, Kannel WB. Atrial fibrillation as an independent risk factor for stroke: the Framingham Study. Stroke. 1991;22:983–988
  2. Lamassa M, Di Carlo A, Pracucci G, Basile AM, Trefoloni G, Vanni P, et al. Characteristics, outcome, and care of stroke associated with atrial fibrillation in Europe: data from a multicenter multinational hospital-based registry (The European Community Stroke Project). Stroke. 2001;32:392–398
  3. Singer DE, Albers GW, Dalen JE, Go AS, Halperin JL, Manning WJ. Antithrombotic therapy in atrial fibrillation. The Seventh ACCP Conference on Antithrombotic Therapy and Thrombolytic Therapy. Chest. 2004;126:429S–456S
  4. Lip GY, Boos C. Antithrombotic therapy for atrial fibrillation. Heart. 2006;92:155–161
  5. Lip GY, Edwards SJ. Stroke prevention with aspirin, warfarin and ximelagatran in patients with non-valvular atrial fibrillation: a systematic review and meta-analysis. Thromb Res. 2006;118:321–333
  6. Hylek EM, Go AS, Chang Y, Jensvold NG, Henault LE, Selby JV, et al. Effect of intensity of oral anticoagulation on stroke severity and mortality in atrial fibrillation. N Engl J Med. 2003;349:1019–1026
  7. Fang MC, Chang Y, Hylek EM, Rosand J, Greenberg SM, Go AS, et al. Advanced age, anticoagulation intensity, and risk for intracranial hemorrhage among patients taking warfarin for atrial fibrillation. Ann Intern Med. 2004;141:745–752
  8. Samsa GP, Matchar DB, Goldstein LB, Bonito AJ, Lux LJ, Witter DM, et al. Quality of anticoagulation management among patients with atrial fibrillation: results of a review of medical records from 2 communities. Arch Intern Med. 2000;160:967–973
  9. Ansell J, Hirsh J, Poller L, Bussey H, Jacobson A, Hylek E. The pharmacology and management of the vitamin K antagonists. The Seventh ACCP Conference on Antithrombotic Therapy and Thrombolytic Therapy. Chest. 2004;126:204S–233S
  10. Bungard TJ, Ghali WA, Teo KK, McAlister FA, Tsuyuki RT. Why do patients with atrial fibrillation not receive warfarin?. Arch Intern Med. 2000;160:41–46
  11. Devereaux PJ, Anderson DR, Gardner MJ, Putnam W, Flowerdew GJ, Brownell BF, et al. Differences between perspectives of physicians and patients on anticoagulation in patients with atrial fibrillation: observational study. BMJ. 2001;323:1218–1222
  12. Man-Son-Hing M, Laupacis A. Anticoagulant-related bleeding in older persons with atrial fibrillation: physicians' fears often unfounded. Arch Intern Med. 2003;163:1580–1586
  13. Bungard TJ, Ghali WA, McAlister FA, Buchan AM, Cave AJ, Hamilton PG, et al. Physicians' perceptions of the benefits and risks of warfarin for patients with nonvalvular atrial fibrillation. CMAJ. 2001;165:301–302
  14. Lip GY, Zarifis J, Watson RD, Beevers DG. Physician variation in the management of patients with atrial fibrillation. Heart. 1996;75(2):200–205
  15. Perez I, Melbourn A, Kalra L. Use of antithrombotic measures for stroke prevention in atrial fibrillation. Heart. 1999;82:570–574
  16. Buckingham TA, Hatala R. Anticoagulants for atrial fibrillation: why is the treatment rate so low?. Clin Cardiol. 2002;25:447–454
  17. Nieuwlaat R, Capucci A, Camm AJ, Olssen SB, Andresen D, Davies DW, et al. on behalf of the Euro Heart Survey Investigators Atrial fibrillation management: a prospective survey in ESC Member Countries: The Euro Heart Survey on Atrial Fibrillation. Eur Heart J. 2005;26:2422–2434
  18. White RH, McBurnie MA, Manolio T, Furberg CD, Gardin JM, Kittner SJ, et al. Oral anticoagulation in patients with atrial fibrillation: adherence with guidelines in an elderly cohort. Am J Med. 1999;106:165–171
  19. Lip GY, Kamath S, Jafri M, Mohammed A, Bareford D. Ethnic differences in patient perceptions of atrial fibrillation and anticoagulation therapy: the West Birmingham Atrial Fibrillation Project. Stroke. 2002;33:238–242
  20. Roche-Nagle G, Chambers F. Evaluation of patient knowledge regarding oral anticoagulants. Ir Med J. 2003;96:211–213
  21. Tang EOYL, Lai CSM, Lee KKC, Wong RSM, Cheng G, Chan TYK. Relationship between patients' warfarin knowledge and anticoagulation control. Ann Pharmacother. 2003;37:34–39
  22. Nadar S, Begum N, Kaur B, Sandhu S, Lip GY. Patients' understanding of anticoagulant therapy in a multiethnic population. J R Soc Med. 2003;96:175–179
  23. Dantas GC, Thompson BV, Manson JA, Tracy S, Upshur REG. Patients' perspectives on taking warfarin: qualitative study in family practice. BMC Fam Pract. 2004;5:15
  24. Taylor FC, Ramsay ME, Tan G, Gabbay J, Cohen H. Evaluation of patients' knowledge about anticoagulant treatment. Qual Health Care. 1994;3:79–85
  25. Lane DA, Ponsford J, Shelley A, Sirpal A, Lip GY. Patient knowledge and perceptions of atrial fibrillation and anticoagulant therapy: effects of an educational intervention programme. The West Birmingham Atrial Fibrillation Project. Int J Cardiol. 2006;110:354–358
  26. Claes N, Buntinx F, Vijgen J, Arnout J, Vermylen J, Fieuws S, et al. The Belgian improved study on oral anticoagulation therapy: a randomized trial. Eur Heart J. 2005;26:2159–2165
  27. Hambleton J. Home monitoring of anticoagulation. J Thromb Thrombolysis. 2002;16:39–42
  28. Murray E, Fitzmaurice D, McCahon D, Fuller C, Sandhur H. Training for patients in a randomised controlled trial of self-management of warfarin treatment. BMJ. 2004;328:437–438
  29. Barcellona D, Contu P, Sorano GG, Pengo V, Maronglu F. The management of oral anticoagulant therapy: the patient's point of view. Thromb Haemost. 2000;83:49–53

PII: S0953-6205(07)00010-6

doi: 10.1016/j.ejim.2006.11.005

European Journal of Internal Medicine
Volume 18, Issue 3 , Pages 202-208 , May 2007

Article Tools

* Image Usage & Resolution