European Journal of Internal Medicine
Volume 18, Issue 6 , Pages 456-462, October 2007

Clinical aspects of cobalamin deficiency in elderly patients. Epidemiology, causes, clinical manifestations, and treatment with special focus on oral cobalamin therapy☆☆

  • Emmanuel Andrès

      Affiliations

    • Department of Internal Medicine, Diabetes and Metabolic Diseases, Hôpitaux Universitaires de Strasbourg, France
    • Corresponding Author InformationCorresponding author. Service de Médecine Interne, Diabète et Maladies Métaboliques, Clinique Médicale B, Hôpitaux Universitaires de Strasbourg, 1 place de l'Hôpital, 67 091 STRASBOURG cedex, France. Tel.: +33 3 88 11 62 59; fax: +33 3 88 11 62 62.
  • ,
  • Josep Vidal-Alaball

      Affiliations

    • National Public Health Service for Wales, UK
    • Department of General Practice, Cardiff University, UK
  • ,
  • Laure Federici

      Affiliations

    • Department of Internal Medicine, Diabetes and Metabolic Diseases, Hôpitaux Universitaires de Strasbourg, France
  • ,
  • Noureddine Henoun Loukili

      Affiliations

    • Department of Infection Control Management, Hôpital Calmette, CHRU de Lille, France
  • ,
  • Jacques Zimmer

      Affiliations

    • Laboratoire d'Immunogénétique-Allergologie, Centre de Recherche Public de la Santé (CRP-Santé), Luxembourg
  • ,
  • Georges Kaltenbach

      Affiliations

    • Department of Internal Medicine and Geriatrics, Hôpitaux Universitaires de Strasbourg, France

Received 21 July 2006; received in revised form 3 November 2006; accepted 22 February 2007. published online 15 July 2007.

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 Funding: The research on cobalamin deficiency was supported by a grant from the Fondation de France (Prix Robert et Jacqueline Zittoun 2004).

☆☆ Contributors: Drafting of the article: E. Andrès and J. Vidal-Alaball. Final approval of the manuscript: E. Andrès, L. J. Vidal-Alaball, Federici, N.H. Loukili, J. Zimmer and G. Kaltenbach.

 Competing interests: No author has any conflict of interest.

PII: S0953-6205(07)00134-3

doi:10.1016/j.ejim.2007.02.013

European Journal of Internal Medicine
Volume 18, Issue 6 , Pages 456-462, October 2007