European Journal of Internal Medicine
Volume 19, Issue 2 , Pages 140-142, March 2008

Pneumocephalus as a complication of multidrug-resistant Klebsiella pneumoniae meningitis☆

  • P. Sreejith

      Affiliations

    • Department of Medicine, Kottayam Medical College, South India-686008
    • ,
  • V. Vishad

      Affiliations

    • Department of Medicine, Kottayam Medical College, South India-686008
    • ,
  • Joseph M. Pappachan

      Affiliations

    • Department of Medicine, Kottayam Medical College, South India-686008
    • Corresponding Author InformationCorresponding author. Tel.: +91 94474 32633.
    • ,
  • D.C. Laly

      Affiliations

    • Department of Medicine, Kottayam Medical College, South India-686008
    • ,
  • R. Jayaprakash

      Affiliations

    • Department of Medicine, Kottayam Medical College, South India-686008
    • ,
  • V.T. Ranjith

      Affiliations

    • Department of Otolaryngology, Kottayam Medical College, South India

Received 20 December 2006; received in revised form 7 March 2007; accepted 9 March 2007. published online 05 October 2007.

Abstract 

Pneumocephalus implies air inside the cranial vault, which usually results from cranio-facial trauma. Occasionally, meningitis caused by gas-forming organisms can result in pneumocephalus. Klebsiella pneumoniae meningitis can, on rare occasions, cause pneumocephalus as a complication. The drug of choice for K. pneumoniae meningitis is a third-generation cephalosporin, and resistance to these drugs is unusual. We report a case of multidrug-resistant K. pneumoniae meningitis resulting from chronic suppurative otitis media, which was later complicated by pneumocephalus. The patient was successfully managed with meropenam and amikacin, the only antibiotics to which these bacilli showed no resistance.

Keywords: Chronic otitis media, Klebsiella pneumoniae, Pneumocephalus

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☆ Declaration: There is no grant support for this work and there are no conflicts of interests among the authors.

PII: S0953-6205(07)00240-3

doi:10.1016/j.ejim.2007.03.021

European Journal of Internal Medicine
Volume 19, Issue 2 , Pages 140-142, March 2008

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