Ethnic variation in certain hematological and biochemical reference intervals in a south Indian healthy adult population

Sundaram, M.; Mohanakrishnan, J.; Murugavel, K.G.; Shankar, E.M.; Solomon, S.; Srinivas, C.N.; Solomon, S.S.; Pulimi, S.; Piwowar-Manning, E.; Dawson, S.; Livant, E.; Kumarasamy, N.; Balakrishnan, P.

doi:10.1016/j.ejim.2007.06.010

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Volume 19, Issue 1 , Pages 46-50, January 2008

Ethnic variation in certain hematological and biochemical reference intervals in a south Indian healthy adult population

M. Sundaram
- YRG Centre for AIDS Research and Education (YRG CARE), Voluntary Health Services Hospital Campus, Taramani, Chennai-600 113, India
J. Mohanakrishnan
- YRG Centre for AIDS Research and Education (YRG CARE), Voluntary Health Services Hospital Campus, Taramani, Chennai-600 113, India
K.G. Murugavel
- YRG Centre for AIDS Research and Education (YRG CARE), Voluntary Health Services Hospital Campus, Taramani, Chennai-600 113, India
E.M. Shankar
- YRG Centre for AIDS Research and Education (YRG CARE), Voluntary Health Services Hospital Campus, Taramani, Chennai-600 113, India
S. Solomon
- YRG Centre for AIDS Research and Education (YRG CARE), Voluntary Health Services Hospital Campus, Taramani, Chennai-600 113, India
C.N. Srinivas
- YRG Centre for AIDS Research and Education (YRG CARE), Voluntary Health Services Hospital Campus, Taramani, Chennai-600 113, India
S.S. Solomon
- YRG Centre for AIDS Research and Education (YRG CARE), Voluntary Health Services Hospital Campus, Taramani, Chennai-600 113, India
S. Pulimi
- YRG Centre for AIDS Research and Education (YRG CARE), Voluntary Health Services Hospital Campus, Taramani, Chennai-600 113, India
E. Piwowar-Manning
- Johns Hopkins University, School of Medicine, Department of Pathology, Baltimore, USA
S. Dawson
- Johns Hopkins University, School of Medicine, Department of Pathology, Baltimore, USA
E. Livant
- Johns Hopkins University, School of Medicine, Department of Pathology, Baltimore, USA
N. Kumarasamy
- YRG Centre for AIDS Research and Education (YRG CARE), Voluntary Health Services Hospital Campus, Taramani, Chennai-600 113, India
P. Balakrishnan
- YRG Centre for AIDS Research and Education (YRG CARE), Voluntary Health Services Hospital Campus, Taramani, Chennai-600 113, India
- Corresponding author. Tel.: +91 44 22542929; fax: +91 44 22542939.

Received 22 January 2007; received in revised form 27 April 2007; accepted 6 June 2007. published online 29 October 2007.

Abstract

Background

We established the biochemical and hematological reference intervals among a south Indian healthy adult population attending an HIV referral centre in Chennai, southern India.

Methods

In a cross sectional study, 213 study subjects (129 male and 84 female) were studied between March and August 2005. All of the parameters were analyzed using standard hematological and biochemical techniques.

Results

Certain biochemical (viz. total bilirubin, alanine transaminase, albumin, creatinine, total protein, lipid profile, creatine phospokinase, uric acid and lactate) and hematological (mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration and lymphocyte levels) parameters presented higher upper limits. In addition, the upper limits of white blood cell count, platelet count, hematocrit, red blood cell count and hemoglobin level were low in comparison to the currently reported ranges.