European Journal of Internal Medicine
Volume 20, Issue 1 , Page 2 , January 2009

“Well done folate, the little boy was born healthy without spina bifida: But will he suffer a stroke when elderly?”

Received 7 February 2008 ,Accepted 12 March 2008.

References 

  1. CDC . Spina bifida and anencephaly before and after folic acid mandate: United States, 1995–1996 and 1999–2000. MMWR Morb Mortal Wkly Rep. 2004;53:362–365
  2. Bayston R, Russell A, Wald NJ, Hoffbrand AV. Folic acid fortification and cancer risk. Lancet. 2007;370(9604):2004
  3. Ntaios GC, Savopoulos CG, Chatzinikolaou AC, Kaiafa GD, Hatzitolios A. Vitamins and stroke: the homocysteine hypothesis still in doubt. Neurologist. 2008;14(1):2–4
  4. Wang X, Qin X, Demirtas H, Li J, Mao G, Huo Y, et al. Efficacy of folic acid supplementation in stroke prevention: a meta-analysis. Lancet. 2007;369(9576):1876–1882
  5. B-Vitamin Treatment Trialists' Collaboration . Homocysteine-lowering trials for prevention of cardiovascular events: a review of the design and power of the large randomized trials. Am Heart J. 2006;151:282–287
  6. Lonn E. Homocysteine in the prevention of ischemic heart disease, stroke and venous thromboembolism: therapeutic target or just another distraction?. Curr Opin Hematol. 2007;14(5):481–487

PII: S0953-6205(08)00111-8

doi: 10.1016/j.ejim.2008.03.015

European Journal of Internal Medicine
Volume 20, Issue 1 , Page 2 , January 2009