European Journal of Internal Medicine
Volume 20, Issue 3 , Pages 280-288 , May 2009

Survey of Cardiovascular Risk Factors in Overweight and Obese Patients (SCOOP Study) Six-month changes in risk factor levels and cardiovascular risk

  • Ido Iori

      Affiliations

    • Dipartimento di Medicina Interna e Specialità Mediche, Azienda Ospedaliera ASMN, Reggio Emilia, Italy
  • ,
  • Giuseppe Fatati

      Affiliations

    • Unità di Diabetologia, Dietetica e Nutrizione Clinica, Ospedale S Maria, Terni, Italy
  • ,
  • Maria Antonia Fusco

      Affiliations

    • Divisione di Dietetica e Nutrizione Clinica, Ospedale S Camillo-Forlanini, Roma, Italy
  • ,
  • Francesco Leonardi

      Affiliations

    • Divisione di Dietetica e Nutrizione Clinica, Ospedale Cannizzaro, Catania, Italy
  • ,
  • Giovanni Matthieu

      Affiliations

    • President FADOI, Medicina Interna, Ospedale E Agnelli, Pinerolo (Torino), Italy
  • ,
  • Giovanni Scanelli

      Affiliations

    • Medicina Interna, Azienda Ospedaliera Arcispedale S Anna, Ferrara, Italy
  • ,
  • Mariapaola Lanti

      Affiliations

    • Associazione per la Ricerca Cardiologica, Roma, Italy
  • ,
  • Alessandro Menotti

      Affiliations

    • Associazione per la Ricerca Cardiologica, Roma, Italy
    • Corresponding Author InformationCorresponding author. Via Latina 49, 00179 Rome, Italy. Tel./fax: +39 06 77591715.

Received 10 January 2008 ,Revised 23 September 2008 ,Accepted 8 October 2008.

References 

  1. World Health Organization . The world health report 2002. Reducing risks, promoting healthy life. Geneva: World Health Organization; 2002;
  2. York DA, Rossner S, Caterson I, Chen CM, James WP, Kumanyika S, et al. Prevention conference VII: obesity, a worldwide epidemic related to heart disease and stroke: Group I: worldwide demographics of obesity. Circulation. 2004;110:463–470
  3. Eckel RH, York DA, Rossner S, Hubbard V, Caterson I, St Jeor ST, et al. Prevention conference VII: obesity, a worldwide epidemic related to heart disease and stroke Executive summary. Circulation. 2004;110:2968–2975
  4. Wilsgaard T, Jacobsen BK, Arnesen E. Determining lifestyle correlates of body mass index using multilevel analyses: the Tromso study, 1979–2001. Am J Epidemiol. 2005;162:1179–1188
  5. Patel MR, Donahue M, Wilson PWF, Califf RM. Clinical trial issues in weight-loss therapy. Am Heart J. 2006;151:633–642
  6. Caterson ID, Hubbard V, Bray GA, Grunstein R, Hansen BC, Hong Y, et al. Prevention Conference VII: obesity, a worldwide epidemic related to heart disease and stroke: Group III: worldwide comorbidities of obesity. Circulation. 2004;110:476–483
  7. De Lusignan S, Haue N, van Vlymen J, Dhoul N, Chan T, Thana L, et al. A study of cardiovascular risk in overweight and obese people in England. Eur J Gen Pract. 2006;12:19–29
  8. Hubert HB, Feinleib M, MacNamara PM, Castelli WP. Obesity as an independent risk factor for cardiovascular disease: a 26-year follow-up of participants in the Framingham Heart Study. Circulation. 1983;67:968–977
  9. Fang J, Wylie-Rosett J, Cohn HW, Kaplan RC, Alderman MH. Exercise, body mass index, caloric intake, and cardiovascular mortality. Am J Prev Med. 2003;25:283–289
  10. Hu G, Tuomilehto J, Silventoinen K, Barengo NC, Peltonen M, Jousilahti P. The effects of physical activity and body mass index on cardiovascular, cancer and all-cause mortality among 47212 middle-aged Finnish men and women. Int J Obes (Lond). 2005;29:894–902
  11. Wilson PW, D'Agostino RB, Sullivan L, Parise H, Kannel WB. Overweight and obesity as determinants of cardiovascular risk: the Framingham experience. Arch Intern Med. 2002;162:1867–1872
  12. Jousilahti P, Tuomilehto J, Vartiainen E, Pekkanen J, Puska P. Body weight, cardiovascular risk factors, and coronary mortality. Circulation. 1996;93:1372–1379
  13. Lakka HM, Lakka TA, Tomilehto J, Salonen JT. Abdominal obesity is associated with increased risk of acute coronary events in men. Eur Heart J. 2002;23:706–713
  14. Hu G, Tuomilehto J, Silventoinen K, Barengo N, Jousilahti P. Joint effects of physical activity, body mass index, waist circumference and waist-to-hip ratio with the risk of cardiovascular disease among middle-aged Finnish men and women. Eur Heart J. 2004;25:2212–2219
  15. Dalton M, Cameron AJ, Zimmt PZ, Shaw JE, Jolley D, Dunstan DW, et al. on behalf of the Ausdiab Committee Waist circumference, waist–hip ratio and body mass index and their correlation with cardiovascular disease risk factors in Australian adults. J Intern Med. 2003;254:555–563
  16. Shaper AG, Wannamethe SG, Walker M. Body weight: implications for the prevention of coronary heart disease, stroke and diabetes mellitus in a cohort of middle-aged men. BMJ. 1997;314:1311–1319
  17. Aravanis C, Blackburn H, Buzina R, Djordjevic BS, Dontas AS, et al. Seven Countries Study. In:  Keys A editors. A multivariate analysis of death and coronary heart disease. Cambridge Mass: Harvard Univ Press; 1980;p. 1–381
  18. Menotti A, Lanti M, Maiani G, Kromhout D. Forty-year mortality from cardiovascular diseases and their risk factors in men of the Italian rural areas of the Seven Countries Study. Acta Cardiol. 2005;60:521–531
  19. Keys A. Longevity of man: relative weight and fatness in middle age. Ann Med. 1989;21:163–168
  20. Haapanen-Niemi N, Miilunpalo S, Pasanen M, Vuori I, Oja P, Malmberg J. Body mass index, physical inactivity and low level of physical fitness as determinants of all-cause and cardiovascular disease mortality — 16 y follow-up of middle-aged and elderly men and women. Int J Obes Relat Metab Disord. 2000;24:1465–1474
  21. Wannamethe SG, Shaper AG, Walker M. Overweight and obesity and weight change in middle-aged men: impact on cardiovascular disease and diabetes. J Epidemiol Community Health. 2005;59:134–139
  22. Jehn ML, Patt MR, Appel LJ, Miller ER. One year follow-up of overweight and obese hypertensive adults following intensive lifestyle therapy. J Hum Nutr Diet. 2006;19:349–354
  23. Douketis JD, Macie C, Thabane L, Williamson DF. Systematic review of long-term weight loss studies in obese adults: clinical significance and applicability to clinical practice. Int J Obes (Lond). 2005;29:1153–1167
  24. Dalle Grave R, Melchionda N, Calugi S, Centis E, Tufano A, Fatati G, et al. Continuous care in the treatment of obesity: and observational multicenter study. J Intern Med. 2005;258:265–273
  25. Tuomilehto J, Lindstrom J, Eriksson JG, Valle TT, Hanalainen H, Ilame-Parikka P, et al. Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance. N Eng J Med. 2001;344:1343–1350
  26. Pan XR, Li GW, Hu YH, Wang JX, Yang WY, An ZX, et al. Effects of diet and exercise in preventing NIDDM in people with impaired glucose tolerance. The Da Qing IGT and Diabetes Study. Diabetes Care. 1997;20:537–544
  27. Buchwald H, Avidor Y, Braunwald E, Jensen MD, Pories W, Fahrbach K, et al. Bariatric surgery: a systematic review and meta-analysis. JAMA. 2005;293:1724–1737
  28. Kligman MD, Dexter DJ, Omer S, Park AE. Shrinking cardiovascular risk through bariatric surgery: application of Framingham risk score in gastric bypass. Surgery. 2008;143:533–538
  29. Rose G, Blackburn H. Cardiovascular Survey Methods. Geneva: World Health Organization; 1968;
  30. Expert Panel on the Detection . Evaluation and Treatment of High Blood cholesterol in Adults: Executive summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). JAMA. 2001;285:2486–2497
  31. Menotti A, Lanti M, Agabiti-Rosei E, Carratelli L, Cavera G, Dormi A, et al. Riskard. New tools for prediction of cardiovascular disease risk derived from Italian population studies. Nutr Metab Cardiovasc Dis. 2005;15:426–440
  32. Giampietro M. L'alimentazione per l'esercizio fisico e lo sport. Roma: Il Pensiero Scientifico Editore Publisher; 2005;
  33. Arienti G. Le basi molecolari della nutrizione. Padova: Piccin Publisher; 2003;
  34. Task Force Obesity Italia . LiGIO'99 Linee Guida Italiane Obesità. Bologna Edizioni: Pendragon Publisher; 1999;
  35. Hellenius ML, de Faire U, Berglund B, Hamsten A, Krakau I. Diet and exercise are equally effective in reducing risk for cardiovascular disease. Results of a randomized controlled study in men with slightly to moderately raised cardiovascular risk factors. Atherosclerosis. 1993;103:81–91
  36. Villareal DT, Miller BV, Banks M, Dontana L, Sinacre DR, Klein S. Effects of lifestyle intervention on metabolic coronary heart disease risk factors in obese older adults. Am J Clin Nutr. 2006;84:1317–1323
  37. Eriksson MK, Westborg CJ, Eliasson MC. A randomized trial of lifestyle intervention in primary healthcare for the modification of cardiovascular risk factors. Scand J Public Health. 2006;34:453–461
  38. Dunn AL, Marcus BH, Kampert JB, Garcia ME, Hohl HW, Blair SN. Reduction in cardiovascular disease risk factors: 6-month results from Project Active. Prev Med. 1997;26:883–892
  39. Katzel LI, Bleecker ER, Colman EG, Rogus EM, Sorkin JD, Goldberg AP. Effects of weight loss vs aerobic exercise training on risk factors for coronary disease in healthy, obese, middle-aged and older men. A randomized controlled trial. JAMA. 1995;274:1915–1921
  40. Miller ER, Erlinger TP, Young DR, Jehn M, Charleston J, Rhodes D, et al. Results of the diet, exercise and weight loss intervention trial (DEW-IT). Hypertension. 2002;40:612–618
  41. Ross R, Dagnone D, Jones PJ, Smith H, Paggads A, Hudson R, et al. Reduction in obesity and related comorbid conditions after diet-induced weight loss or exercise-induced weight loss in men. A randomized, controlled trial. Ann Intern Med. 2000;133:92–103
  42. Nicklas BJ, Dennis KE, Berman DM, Sorkin J, Ryan AS, Goldberg AP. Lifestyle intervention of hypocaloric dieting and walking reduces abdominal obesity and improves coronary heart disease risk factor in obese, postmenopausal, African–American and Caucasian women. J Gerontol A Biol Sci Med Sci. 2003;58:181–189
  43. Esposito K, Pontillo A, Di Palo C, Giugliano G, Masella G, Marfella R, et al. Effect of weight loss and lifestyle changes on vascular inflammatory markers in obese women: a randomized trial. JAMA. 2003;289:1799–1804
  44. Carels RA, Darby LA, Cacciapaglia HM Douglass OM. Reducing cardiovascular risk factors in postmenopausal women through a lifestyle change intervention. J Wemn Health (Larchmt). 2004;13:412–426
  45. Karvetti RL, Hakala P. A seven-year follow-up of a weight reduction programme in Finnish primary health care. Eur J Clin Nutr. 1992;46:743–752
  46. Baigent C, Keech A, Kearney PM, Blackwell L, Buck G, Pollicino C, et al. Cholesterol Treatment Trialists' (CTT) Collaborators Efficacy and safety of cholesterol-lowering treatment: prospective meta-analysis of data from 90,056 participants in 14 randomized trials of statins. Lancet. 2005;366:1267–1278
  47. Turnbull F Blood pressure treatment trialists' Collaboration. Effects of different blood-pressure-lowering regimen on major cardiovascular events: results of prospective-designed overviews of randomized trials. Lancet. 2003;362:1527–1535

PII: S0953-6205(08)00275-6

doi: 10.1016/j.ejim.2008.10.001

European Journal of Internal Medicine
Volume 20, Issue 3 , Pages 280-288 , May 2009