European Journal of Internal Medicine
Volume 21, Issue 2 , Pages 101-103 , April 2010

Persistency of low levels of anticardiolipin and anti-Beta2 Glycoprotein1 in thrombosis

  • Marta Amaral

      Affiliations

    • Autoimmune Diseases Unit, Curry Cabral Hospital, Lisbon, Portugal
    • Pharmacology Department, Faculty of Medical Sciences, Lisbon, Portugal
    • Corresponding Author InformationCorresponding author. Pharmacology Department, Faculty of Medical Sciences, New University of Lisbon, Campo Mártires da Pátria, 130, 1169-056 Lisboa, Portugal. Tel.: +351 21 880 3035; fax: +351 21 880 3083.
    • ,
  • Catarina Favas

      Affiliations

    • Autoimmune Diseases Unit, Curry Cabral Hospital, Lisbon, Portugal
    • ,
  • José Delgado Alves

      Affiliations

    • Pharmacology Department, Faculty of Medical Sciences, Lisbon, Portugal
    • Department of Medicine IV, Fernando Fonseca Hospital, Amadora, Portugal

Received 26 August 2009 ,Revised 28 November 2009 ,Accepted 17 December 2009.

References 

  1. Marai I, Tincani A, Balestrieri G, Shoenfeld Y. Anticardiolipin and anti-beta-2-glycoprotein antibodies. Autoimmunity. 2005;38:33–38
  2. Roubey RA. Autoantibodies to phospholipids-binding plasma proteins: a new view of lupus anticoagulants and other “antiphospholipid” antibodies. Blood. 1994;84:2854–2867
  3. Dunn AS, Kaboli P, Halfdanarson T, et al. Do patients followed in anticoagulation clinics for antiphospholipid syndrome meet the criteria for the disorder?. Thromb Haemost. 2005;94:548–554
  4. Miyakis S, Lockshin MD, Atsumi T, et al. International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS). J Thromb Haemost. 2006;4:295–306
  5. Petri M. Epidemiology of the antiphospholipid antibody syndrome. J Autoimmun. 2000;15:145–151
  6. Levine JS, Branch DW, Rauch J. The antiphospholipid syndrome. N Engl J Med. 2002;346:752–763
  7. Delgado Alves J, Ames PRJ. Atherosclerosis, oxidative stress and auto-antibodies in systemic lupus eryhtematosus and primary antiphospholipid syndrome. Immunobiology. 2003;207:23–28
  8. Cervera R, Piette JC, Font J, et al. Antiphospholipid syndrome: clinical and immunologic manifestations and patterns of disease expression in a cohort of 1000 patients. Arthritis Rheum. 2002;46:1019–1027
  9. Ginsburg KS, Liang MH, Newcomer L, et al. Anticardiolipin antibodies and the risk for ischemic stroke and venous thrombosis. Ann Intern Med. 1992;117:997–1002

PII: S0953-6205(09)00265-9

doi: 10.1016/j.ejim.2009.12.010

European Journal of Internal Medicine
Volume 21, Issue 2 , Pages 101-103 , April 2010

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