European Journal of Internal Medicine
Volume 23, Issue 3 , Page e77 , April 2012

Clinical trial data provides hope for attenuation of mucosal injury in coeliac disease

  • Laura Crespo Pérez

      Affiliations

    • Hospital Universitario Ramón y Cajal, Madrid, Spain
    • Corresponding Author InformationCorresponding author at: Hospital Universitario Ramón y Cajal, Madrid, Carretera de Colmenar, Km. 9100, 28034, Madrid, Spain. Tel.: +34 913368354, +34 913368771; fax: +34 913368354.
    • ,
  • Francisco León

      Affiliations

    • Centocor, Malvern, Pennsylvania, USA

Received 16 December 2011 ,Accepted 19 December 2011.

References 

  1. Non-dietary therapeutic clinical trials in coeliac disease. Crespo L, Castillejo G, Cano A, León F. Eur J Intern Med 23 (1) (2012) 9–14.
  2. ALV003, a novel glutenase, attenuates gluten-induced small intestinal mucosal injury in coeliac disease patients: A randomized controlled phase 2a clinical trial. Lähdeaho ML, Kaukinen K, Laurila K, Marcantonio A, Adelman D, Mäki MM. Abstract OP050B, United European Gastroenterology Week conference (UEGW 2011), Stockholm, Sweden, October 2011. Manuscript in preparation.
  3. Larazotide Acetate in Patients With Active Coeliac Disease: A Randomized, Double-Blind, Placebo-Controlled Study. Murray JA, Fedorak RN, DiMarino A, Green PHR, Pluta H, Crespo L, León F, Jiang J, Wu TT. Manuscript in preparation.

PII: S0953-6205(11)00315-3

doi: 10.1016/j.ejim.2011.12.008

European Journal of Internal Medicine
Volume 23, Issue 3 , Page e77 , April 2012

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