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Article Title |
Author(s) |
Type (Status) |
Available Online |
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Contribution of Hla-B51 in the susceptibility and specific clinical features of Behcet's disease in Tunisian patients
DOI: 10.1016/j.ejim.2011.12.011
Abstract: Background: Many researchers have tried to investigate the association of HLA-B51 with the severity and the clinical features of BD with conflicting results. Methods: We aimed at investigati...
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Amira Hamzaoui,
Mohamed Habib Houman,
Meriem Massouadia,
Thouraya Ben Salem,
Monia Smiti Khanfir,
Imed Ben Ghorbel,
Mohamed Miled
et al.
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Full-length article
(In Press Corrected Proof)
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30 January 2012 |
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Changes in body mass index on a gluten-free diet in coeliac disease: A nationwide study
DOI: 10.1016/j.ejim.2011.12.012
Abstract: Objective: The clinical presentation of coeliac disease has changed and patients are often overweight at diagnosis. There is concern that patients might gain further weight while on a gluten...
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Anniina Ukkola,
Markku Mäki,
Kalle Kurppa,
Pekka Collin,
Heini Huhtala,
Leila Kekkonen,
Katri Kaukinen
et al.
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Full-length article
(In Press Corrected Proof)
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30 January 2012 |
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Time to change the glomerular filtration rate estimating formula in primary care?
DOI: 10.1016/j.ejim.2012.01.001
Abstract: Background: The most commonly used equation for estimated glomerular filtration rate (eGFR) is nowadays the four-variable Modification of Diet in Renal Disease (MDRD) equation. This formula ...
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Päivi E. Korhonen,
Hannu Kautiainen,
Salme Järvenpää,
Sirkka-Liisa Kivelä
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Full-length article
(In Press Corrected Proof)
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30 January 2012 |
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Fibrates: Therapeutic potential for diabetic nephropathy?
DOI: 10.1016/j.ejim.2011.12.007
Abstract: Despite intensive glucose-lowering treatment and advanced therapies for cardiovascular risk factors, such as hypertension and dyslipidaemia, diabetes mellitus with its macro- and microvascul...
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I. Kouroumichakis,
N. Papanas,
P. Zarogoulidis,
V. Liakopoulos,
E. Maltezos,
D.P. Mikhailidis
et al.
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Short survey
(In Press Corrected Proof)
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19 January 2012 |
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Evaluation of transient hyperglycemia in non-diabetic patients with febrile neutropenia
DOI: 10.1016/j.ejim.2011.12.010
Abstract: Background: We aimed to examine the effect of transient hyperglycemia in non-diabetic patients with febrile neutropenia. Methods: A total of 86 patients with febrile neutropenia were evaluat...
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Dilek Ersil Soysal,
Volkan Karakus,
Ali Rıza Seren,
Erhan Tatar,
Mustafa Celik,
Sezin Hızar
et al.
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Full-length article
(In Press Corrected Proof)
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19 January 2012 |
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Clinical trial data provides hope for attenuation of mucosal injury in coeliac disease
DOI: 10.1016/j.ejim.2011.12.008
Our review article on therapeutic clinical trials in coeliac disease , published on-line in EJIM in September 2011, is partially obsolete even before its publication in print. We have been made aware ...
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Laura Crespo Pérez,
Francisco León
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Correspondence
(In Press Corrected Proof)
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18 January 2012 |
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Limitations of gammaglutamyl transaminase as an indicator of biliary obstruction
DOI: 10.1016/j.ejim.2011.12.009
When levels of serum alkaline phosphatase(ALP), serum bilirubin, and serum gamma glutamyly transaminase(GGT) fluctuate in a patient in whom suspected choledocholithiasis(CDL) is associated with non-di...
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Oscar M.P. Jolobe
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Correspondence
(In Press Corrected Proof)
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18 January 2012 |
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Did British Royal Navy actually report scurvy in 1747?
DOI: 10.1016/j.ejim.2011.12.004
We read with interest Baron's letter commenting on our review article on the history of scurvy . We hereby reply to the comments made by Baron and we would like to thank the author for the opportunity...
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Apostolos I. Beloukas,
Aristidis Diamantis,
Emmanouil Magiorkinis
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Correspondence
(In Press Corrected Proof)
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09 January 2012 |
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Limitations of gammaglutamyl transaminase as an indicator of biliary obstruction. Reply by the authors
DOI: 10.1016/j.ejim.2011.12.005
We read with interest the comments made by Jolobe OMP: “Limitations of gammaglutamyl transaminase as an indicator of biliary obstruction” . The author raised some interesting points and I would like t...
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Predrag Jovanovic,
Nermin Salkic,
Enver Zerem,
Farid Ljuca
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Correspondence
(In Press Corrected Proof)
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09 January 2012 |
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Seasonal variations of systemic lupus erythematosus flares in southern France
DOI: 10.1016/j.ejim.2011.12.006
Abstract: Objective: Exposure to sunlight is one of the environmental factors involved in the pathogenesis of systemic lupus erythematosus. We investigated whether there is seasonal variation in the i...
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Laurent Chiche,
Noémie Jourde,
Claire Ulmann,
Julien Mancini,
Albert Darque,
Nathalie Bardin,
Marie-Pierre Dicostanzo,
Guillemette Thomas,
Jean-Robert Harlé,
Julien Vienne,
Harilaos Loukos,
Charleric Bornet
et al.
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Full-length article
(In Press Corrected Proof)
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09 January 2012 |
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High prevalence of polymorphism and low activity of thiopurine methyltransferase in patients with inflammatory bowel disease
DOI: 10.1016/j.ejim.2011.12.002
Abstract: Background: Gene polymorphism of thiopurine methyltransferase (TPMT) correlates with decreased enzyme activity which determines a significant risk of adverse effect reactions (ADR) in patien...
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Tiziana Larussa,
Evelina Suraci,
Margherita Lentini,
Immacolata Nazionale,
Luigia Gallo,
Ludovico Abenavoli,
Maria Imeneo,
Francesco Saverio Costanzo,
Giovanni Cuda,
Francesco Luzza
et al.
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Full-length article
(In Press Corrected Proof)
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09 January 2012 |
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Clinical remission or mucosal healing: A therapeutic dilemma of ulcerative colitis
DOI: 10.1016/j.ejim.2011.12.003
I read with great interest the recent article by Lopez-Palacios et al. . I appreciate the authors for the important results of their study. There are some issues to be considered. The authors pointed ...
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Levent Filik
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Correspondence
(In Press Corrected Proof)
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05 January 2012 |
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The physiological significance and potential clinical applications of ghrelin
DOI: 10.1016/j.ejim.2011.12.001
Abstract: Ghrelin, a natural ligand for the growth hormone (GH)-secretagogue receptor (GHS-R), is now known to play a role in a number of different physiological processes. For example, ghrelin increa...
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Takashi Akamizu,
Kenji Kangawa
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Short survey
(In Press Corrected Proof)
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03 January 2012 |
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From stress to functional syndromes: An internist's point of view
DOI: 10.1016/j.ejim.2011.11.016
Abstract: In this brief review we address schematically the relationship between two emerging issues in clinical medicine: stress and functional syndromes. It is becoming increasingly clear that they ...
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Daniela Lucini,
Massimo Pagani
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Short survey
(In Press Corrected Proof)
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26 December 2011 |
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Infectious complications of chemotherapy in clinically aggressive mature B and T cell lymphomas
DOI: 10.1016/j.ejim.2011.11.018
Abstract: Background: Scientific literature on infectious complications of chemotherapy in lymphomas is often based on retrospective studies or clinical trials performed with selected patients. This p...
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Juan José Alonso,
Araceli Cánovas,
José Guillermo Barreiro,
Ciriaco Aguirre
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Full-length article
(In Press Corrected Proof)
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23 December 2011 |
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Chloride: The queen of electrolytes?
DOI: 10.1016/j.ejim.2011.11.013
Abstract: Background: Channelopathies, defined as diseases that are caused by mutations in genes encoding ion channels, are associated with a wide variety of symptoms and have been documented extensiv...
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Kenrick Berend,
Leonard Hendrik van Hulsteijn,
Rijk O.B. Gans
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Short survey
(In Press Corrected Proof)
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23 December 2011 |
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Pseudo-myelofibrosis: A new clinical entity
DOI: 10.1016/j.ejim.2011.11.014
Primary myelofibrosis (MF) is an established clinical entity due to a clonal disorder of myeloid stem cells. The major diagnostic demonstration rests on the presence of fibrosis of the bone marrow, me...
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Ettore Bartoli,
Daniele Sola,
Pier Paolo Sainaghi,
Luca Rossi,
Renzo Boldorini
et al.
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Correspondence
(In Press Corrected Proof)
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19 December 2011 |
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Venous thromboembolism prophylaxis of acutely ill hospitalized medical patients. Are we over-treating our patients?
DOI: 10.1016/j.ejim.2011.11.006
Abstract: Venous thromboembolism (VTE) is prevalent and is associated with dire consequences. Many VTE events are related to medical hospitalization, and some of these events are avoidable when approp...
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Moshe Vardi,
Michal Haran
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Discussion
(In Press Corrected Proof)
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19 December 2011 |
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The effects of low-dose fluvastatin and valsartan combination on arterial function: A randomized clinical trial
DOI: 10.1016/j.ejim.2011.11.011
Abstract: Background: Ageing progressively diminishes arterial functions, even in the absence of traditional risk factors. Our aim was to explore whether age-related arterial changes in middle-aged ma...
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Mojca Lunder,
Miodrag Janić,
Borut Jug,
Mišo Šabovič
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Full-length article
(In Press Corrected Proof)
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14 December 2011 |
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Can we consider the right hepatic lobe size/albumin ratio a noninvasive predictor of oesophageal varices in hepatitis C virus-related liver cirrhotic Egyptian patients?
DOI: 10.1016/j.ejim.2011.11.010
Abstract: Background: The current guidelines recommend the screening of all cirrhotic patients by endoscopy, but repeated endoscopic examinations are unpleasant for patients and have a high cost impac...
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Serag Esmat,
Dalia Omarn,
Laila Rashid
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Full-length article
(In Press Corrected Proof)
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12 December 2011 |
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Venous thromboembolism prophylaxis of acutely ill hospitalized medical patients. Are we under-treating our patients?
DOI: 10.1016/j.ejim.2011.11.005
Abstract: Venous thromboembolism (VTE) is frequent in patients hospitalized in Internal Medicine wards. It carries a considerable morbidity and mortality. Recommendations for use of anticoagulation ar...
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Batia Roth-Yelinek
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Discussion
(In Press Corrected Proof)
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08 December 2011 |
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Respiratory High-Dependency Care Units for the burden of acute respiratory failure
DOI: 10.1016/j.ejim.2011.11.002
Abstract: The burden of acute respiratory failure (ARF) has become one of the greatest epidemiological challenges for the modern health systems. Consistently, the imbalance between the increasing prev...
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Raffaele Scala
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Short survey
(In Press Corrected Proof)
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02 December 2011 |
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KCNJ11 gene E23K variant and therapeutic response to sulfonylureas
DOI: 10.1016/j.ejim.2011.10.018
Abstract: Aims: Potassium inwardly rectifier 6.2 subunit (Kir6.2) of the ATP-sensitive potassium (KATP) channel encoded by KCNJ11 gene is a therapeutical target for sulfonylureas. KCNJ11 E23K polymorp...
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Martin Javorsky,
Lucia Klimcakova,
Zbynek Schroner,
Jozef Zidzik,
Eva Babjakova,
Maria Fabianova,
Miriam Kozarova,
Ruzena Tkacova,
Jan Salagovic,
Ivan Tkac
et al.
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Full-length article
(In Press Corrected Proof)
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28 November 2011 |
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Lupus: Novel therapies in clinical development
DOI: 10.1016/j.ejim.2011.11.001
Abstract: There have been significant advancements in understanding the immunopathogenesis of systemic lupus erythematosus. However, the developments in therapeutics have been rather slow. Belimumab, ...
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Preeta Kaur Chugh
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Short survey
(In Press Corrected Proof)
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28 November 2011 |
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Hematocrit, urea and gender: The Hematocrit, Urea and GEnder formula for prognosing progressive renal failure in diabetic nephropathy
DOI: 10.1016/j.ejim.2011.10.014
Abstract: Objective: Diabetic nephropathy is a common cause of end stage renal disease. Notwithstanding, wide inter-individual variations in the speed of progression of diabetic nephropathy are freque...
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Nicolás Roberto Robles,
Flavio Ferreira,
Rocio Martinez-Gallardo,
Joaquin Alvarez Gregori,
Emilio Sanchez-Casado,
Juan Jose Cubero,
Juan Macias
et al.
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Full-length article
(In Press Corrected Proof)
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21 November 2011 |
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D-dimer levels in assessing severity and clinical outcome in patients with community-acquired pneumonia. A secondary analysis of a randomised clinical trial
DOI: 10.1016/j.ejim.2011.10.019
Abstract: Background: D-dimer levels are in several studies elevated in patients with CAP. In this study we assess the use of D-dimer levels and its association with severity assessment and clinical o...
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Dominic Snijders,
Margreet Schoorl,
Marianne Schoorl,
Piet C. Bartels,
Tjip S. van der Werf,
Wim G. Boersma
et al.
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Full-length article
(In Press Corrected Proof)
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21 November 2011 |
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Sleep disorders in morbid obesity
DOI: 10.1016/j.ejim.2011.10.016
Abstract: The increasing prevalence of obesity has lead to an increase in the prevalence of sleep disordered breathing in the general population. The disproportionate structural characteristics of the...
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Morohunfolu E. Akinnusi,
Ranime Saliba,
Jahan Porhomayon,
Ali A. El-Solh
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Short survey
(In Press Corrected Proof)
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21 November 2011 |
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Mortality in Cushing's syndrome: A systematic review and meta-analysis
DOI: 10.1016/j.ejim.2011.10.013
Abstract: Context: Data on mortality associated with Cushing's disease (CD) and Cushing's syndrome (CS) are scarce. Objective: To perform a systematic review and meta-analysis of mortality studies in ...
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D. Graversen,
P. Vestergaard,
K. Stochholm,
C.H. Gravholt,
J.O.L. Jørgensen
et al.
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Full-length article
(In Press Corrected Proof)
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16 November 2011 |
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The role of radix hedysari polysaccharide on the human umbilical vein endothelial cells induced by high glucose
DOI: 10.1016/j.ejim.2011.10.006
Abstract: Background: Diabetes mellitus can cause a wide variety of vascular complications and it is one of the major risk factors for cardiovascular diseases (CVD). High glucose can induce vascular e...
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Jing Liu,
Wenjuan Deng,
Lei Fan,
Limin Tian,
Liying Jin,
Zhisheng Jin,
Qian Guo,
Yanjia Xu,
Ning Li
et al.
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Full-length article
(In Press Corrected Proof)
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10 November 2011 |
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Optimal drug therapy after aspirin-induced upper gastrointestinal bleeding
DOI: 10.1016/j.ejim.2011.10.004
Abstract: Upper gastrointestinal bleeding is a common adverse effect of chronic aspirin treatment. Traditionally, most physicians might tend to discontinue aspirin therapy after related gastrointestin...
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M. Struijk,
D.F. Postma,
S.A.C. van Tuyl,
M.A. van de Ree
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Short survey
(In Press Corrected Proof)
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07 November 2011 |
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Sepsis-induced acute respiratory distress syndrome with fatal outcome is associated to increased serum transforming growth factor beta-1 levels
DOI: 10.1016/j.ejim.2011.10.001
Abstract: Background: TGF-β1 is a promoter of pulmonary fibrosis in many chronic inflammatory diseases. TGF-β1 circulating levels in patients with sepsis-induced Acute Respiratory Distress Syndrome (A...
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Raúl de Pablo,
Jorge Monserrat,
Eduardo Reyes,
David Díaz,
Manuel Rodríguez-Zapata,
Antonio de la Hera,
Alfredo Prieto,
Melchor Álvarez-Mon
et al.
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Full-length article
(In Press Corrected Proof)
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07 November 2011 |
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Can we use severity assessment tools to increase outpatient management of community-acquired pneumonia?
DOI: 10.1016/j.ejim.2011.10.002
Abstract: Outpatient management of community-acquired pneumonia (CAP) has several potential advantages, including significant cost-savings, a reduction in hospital-acquired infections and increased pa...
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James D. Chalmers,
Julia Rutherford
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Short survey
(In Press Corrected Proof)
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04 November 2011 |
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Did Lind perform a clinical trial of scurvy in 1747?
DOI: 10.1016/j.ejim.2011.09.007
In their recent review article Magiorkinis, Beloukas and Diamantis were apparently unaware of three critical papers on James Lind's published trial on treatment of scurvy with oranges and lemons .
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Jeremy Hugh Baron
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Correspondence
(In Press Corrected Proof)
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24 October 2011 |
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Prognostic value of low and high ankle-brachial index in hospitalized medical patients
DOI: 10.1016/j.ejim.2011.09.004
Abstract: Background: Peripheral arterial disease (PAD) is frequently underdiagnosed in the clinical practice, leading to a lack of opportunity to detect subjects at a high risk for cardiovascular (CV...
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Leonella Pasqualini,
Giuseppe Schillaci,
Matteo Pirro,
Gaetano Vaudo,
Christian Leli,
Renato Colella,
Salvatore Innocente,
Giovanni Ciuffetti,
Elmo Mannarino
et al.
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Full-length article
(In Press Corrected Proof)
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07 October 2011 |
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Residual pulmonary thromboemboli after acute pulmonary embolism
DOI: 10.1016/j.ejim.2011.08.018
Abstract: Background: After an acute pulmonary embolism (PE), the complete resolution of thromboemboli may not be routinely achieved. The rate of persistence may depend on the time and the diagnostic ...
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José Luis Alonso-Martínez,
Francisco Javier Anniccherico-Sánchez,
Miren Aránzazu Urbieta-Echezarreta,
José Luis García-Sanchotena,
Helena Gómez Herrero
et al.
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Full-length article
(In Press Corrected Proof)
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12 September 2011 |
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Low dose or high dose of proton pump inhibitor for ulcer bleeding?
DOI: 10.1016/j.ejim.2011.08.015
I am interested in one recent paper “Comparison of infusion or low-dose proton pump inhibitor treatments in upper gastrointestinal system bleeding” in the European Journal of Internal Medicine . Songü...
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Hwai-Jeng Lin
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Correspondence
(In Press Corrected Proof)
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05 September 2011 |
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Hypovitaminosis D: Don't forget dementia
DOI: 10.1016/j.ejim.2011.07.021
Recently, Makariou et al. reported the results of an interesting literature review in which the “novel roles of vitamin D in disease” were studied. Based on a non-systematic method, the authors did a...
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Cédric Annweiler,
Olivier Beauchet
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Correspondence
(In Press Corrected Proof)
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01 September 2011 |
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Publisher's note
DOI: 10.1016/j.ejim.2011.08.012
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Publisher's note
(In Press Corrected Proof)
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17 August 2011 |
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Reprint of: Detrimental action of thiazolidinediones on bone (rebuttal)
DOI: 10.1016/j.ejim.2011.08.007
Dr. Mascitelli and colleagues raise an important problem. At the time our review was written and accepted, data on bone problems were not known to us. In Table 2 of our article, we adapted a table fro...
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J.W.F. Elte,
J.F. Blicklé
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Correspondence
(In Press Corrected Proof)
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16 August 2011 |
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Reprint of: Differential diagnosis by laboratory medicine: a quick reference for physicians
DOI: 10.1016/j.ejim.2011.08.008
This reference book is divided into four parts: Introduction to laboratory medicine; biochemical/laboratory parameters in biological materials; biochemical/laboratory findings in clinical units and co...
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J.W.F. Elte
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Book review
(In Press Corrected Proof)
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16 August 2011 |
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Reprint of: Diagnosis of Cushing's syndrome
DOI: 10.1016/j.ejim.2011.08.001
The diagnosis of Cushing's syndrome (CS), including pituitary-dependent CS (Cushing's disease), adrenal CS (adenoma, carcinoma, hyperplasia), ectopic and iatrogenic CS, is easy as long as it presents ...
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J.W.F. Elte
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Editorial
(In Press Corrected Proof)
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16 August 2011 |
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Reprint of: Bone metastasis of a follicular thyroid carcinoma originated in a toxic multinodular goiter
DOI: 10.1016/j.ejim.2011.08.006
Follicular thyroid carcinoma is the second most common thyroid malignancy, accounting for 5–15% of such tumours . Because physical examination does not differentiate between benign and malignant nodul...
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T.S. Schmitt,
J.W.F. Elte,
A.P. Rietveld,
H.C.T. van Zaanen,
M. Castro Cabezas
et al.
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Short communication
(In Press Corrected Proof)
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16 August 2011 |
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Reprint of: Proposal for a multidisciplinary approach to the patient with morbid obesity: The St. Franciscus Hospital Morbid Obesity Program
DOI: 10.1016/j.ejim.2011.08.003
Abstract: Morbid obesity is a serious disease as it is accompanied by substantial co-morbidity and mortality. The prevalence is increasing to an alarming extent, in Europe as well as in the United Sta...
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J.W.F. Elte,
M. Castro Cabezas,
W.W. Vrijland,
C.H. Ruseler,
M. Groen,
G.H.H. Mannaerts
et al.
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Review article
(In Press Corrected Proof)
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16 August 2011 |
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Reprint of: Peripheral arterial disease: A growing problem for the internist
DOI: 10.1016/j.ejim.2011.08.004
Abstract: The atherothrombotic conditions, coronary artery disease, cerebrovascular disease and peripheral arterial disease (PAD), together account for almost one-half of all deaths in Europe each yea...
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Coen D.A. Stehouwer,
Denis Clement,
Christopher Davidson,
Curt Diehm,
Jan Willem Elte,
Marc Lambert,
Daniel Sereni,
for the EFIM Vascular Medicine Working Group
et al.
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Review article
(In Press Corrected Proof)
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16 August 2011 |
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Reprint of: The history of the (Young) AEMI(E) and the EFIM
DOI: 10.1016/j.ejim.2011.08.005
Abstract: The European Federation of Internal Medicine (EFIM) was formed in 1996 through a merger between the Association Européenne de Médicine Interne (d' Ensemble) (AEMI(E)) and the Forum of Presid...
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Ugo E.F. Carcassi,
Jan Willem F. Elte,
Christopher Davidson
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Full-length article
(In Press Corrected Proof)
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16 August 2011 |
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Reprint of: Thiazolidinediones for the treatment of type 2 diabetes
DOI: 10.1016/j.ejim.2011.08.002
Abstract: Thiazolidinediones (TZD), or glitazones, represent a new generation of antidiabetic drugs that have recently been introduced in Europe. They improve insulin resistance, one of the key anomal...
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J.W.F. Elte,
J.F. Blicklé
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Review article
(In Press Corrected Proof)
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16 August 2011 |