Abstract
Aims
Vascular risk equations are tools used to help prevent cardiovascular events. Our
aim was to compare the REGICOR and SCORE equations in a general population and in
persons with the metabolic syndrome (MS) according to the criteria of the International
Diabetes Federation.
Methods and results
We calculated the cardiovascular risk with both equations in a random sample of 838
non-diabetic persons aged 40–65 years without a history of cardiovascular disease, of whom 251 had the MS. Of the
838 persons, 3.6% had a high risk according to SCORE and 1.5% according to REGICOR,
and of these, 53.3% and 61.5%, respectively, had the MS. The mean risk was greater
in the persons with the MS than those without (REGICOR 4.6% vs. 2.6% and SCORE 1.7%
vs. 1%; p<0.01 for each). In comparison with the group without the MS, the percentage of persons
with the MS who had a high risk was greater with both scales: REGICOR (3.2% vs. 0.8%,
p=0.027) and SCORE (6.4% vs. 2.4%, p=0.004). The agreement (kappa index) classifying the subjects with a high risk, was 0.453 in the overall sample
and 0.391 in the subgroup with the MS.
Conclusions
The percentage of persons classified as having a high cardiovascular risk differed
between REGICOR and SCORE. Using these scales only a small percentage of non-diabetic
persons with the MS have a high risk. The presence of the MS multiplies the percentage
of non-diabetic persons with a high vascular risk two-fold with SCORE and four-fold
with REGICOR.
Keywords
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Article info
Publication history
Published online: March 26, 2012
Accepted:
February 27,
2012
Received in revised form:
February 8,
2012
Received:
November 27,
2011
Identification
Copyright
© 2012 European Federation of Internal Medicine. Published by Elsevier Inc. All rights reserved.
