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Geriatric assessment and chronic kidney disease in the oldest old: The Octabaix study

  • Francesc Formiga
    Correspondence
    Corresponding author at: Geriatric Unit, Internal Medicine Service, Hospital Universitari de Bellvitge, L'Hospitalet de Llobregat, 08907 Barcelona, Spain. Tel.: +34 93 260 7419; fax: +34 93 260 7420.
    Affiliations
    Geriatric Unit, Internal Medicine Service, Hospital Universitari de Bellvitge, L'Hospitalet de Llobregat, Barcelona, Spain

    Laboratori Clínic L'Hospitalet-Cornellà, Barcelona, Spain
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  • Assumpta Ferrer
    Affiliations
    Primary Healthcare Centre ‘El Plà’ CAP-I, Sant Feliu de Llobregat, Barcelona, Spain
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  • Josep Maria Cruzado
    Affiliations
    Bellvitge Biomedical Research Institute, IDIBELL, L'Hospitalet de Llobregat, Barcelona, Spain

    Laboratori Clínic L'Hospitalet-Cornellà, Barcelona, Spain
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  • Gloria Padros
    Affiliations
    Nephrology Department, Hospital Universitari de Bellvitge, L'Hospitalet de Llobregat, Barcelona, Spain
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  • Marta Fanlo
    Affiliations
    Geriatric Unit, Internal Medicine Service, Hospital Universitari de Bellvitge, L'Hospitalet de Llobregat, Barcelona, Spain
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  • Beatriz Roson
    Affiliations
    Geriatric Unit, Internal Medicine Service, Hospital Universitari de Bellvitge, L'Hospitalet de Llobregat, Barcelona, Spain

    Laboratori Clínic L'Hospitalet-Cornellà, Barcelona, Spain
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  • Ramón Pujol
    Affiliations
    Geriatric Unit, Internal Medicine Service, Hospital Universitari de Bellvitge, L'Hospitalet de Llobregat, Barcelona, Spain

    Laboratori Clínic L'Hospitalet-Cornellà, Barcelona, Spain
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Published:March 29, 2012DOI:https://doi.org/10.1016/j.ejim.2012.03.009

      Abstract

      Background

      The prevalence of chronic kidney disease (CKD) in older people is increasing.
      We determine the proportion of CKD in a sample of 321, 85-year-old community-dwelling subjects, and assess the association of socio-demographic data, global geriatric assessment data and comorbidity with CKD according to the estimated glomerular filtration rate (eGFR) of subjects.

      Methods

      Serum creatinine, eGFR (derived in ml/min/1.73 m2 using the Modification of Diet in Renal Disease formula), socio-demographic variables, the Barthel Index (BI), the Spanish version of the Mini-Mental State Examination (MEC), the Mini Nutritional Assessment (MNA), the Charlson Index, the Gait Rating Scale, social risk, quality of life and prevalent chronic diseases were collected.

      Results

      CKD prevalence was 56.7% for eGFR<60 ml/min/1.73 m2, 19.9% for eGFR<45 ml/min/1.73 m2 and 6.6% for GFR<30 ml/min/1.73 m2. Multiple logistic regression analysis showed that a prior diagnosis of hypertension was associated with an eGFR<60 ml/min/1.73 m2 (p<0.008, OR 2.134, 95% CI 1.216–3.744). A diagnosis of heart failure (p<0.001, OR 3.610, 95% CI 1.677–7.771) and a poor score on the quality of life measure (p<0.008, OR 0.9660, 95% CI 0.966–0.995) were associated with an eGFR<45 ml/min/1.73 m2.

      Conclusions

      More than half of the oldest old in this study had an eGFR<60 ml/min/1.73 m2. A history of hypertension was associated with CKD. The group of patients with an eGFR<45 ml/min/1.73 m2 was associated with a diagnosis of heart failure and a worse quality of life.

      Keywords

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