Abstract
Background
The prevalence of chronic kidney disease (CKD) in older people is increasing.
We determine the proportion of CKD in a sample of 321, 85-year-old community-dwelling
subjects, and assess the association of socio-demographic data, global geriatric assessment
data and comorbidity with CKD according to the estimated glomerular filtration rate
(eGFR) of subjects.
Methods
Serum creatinine, eGFR (derived in ml/min/1.73 m2 using the Modification of Diet in Renal Disease formula), socio-demographic variables,
the Barthel Index (BI), the Spanish version of the Mini-Mental State Examination (MEC),
the Mini Nutritional Assessment (MNA), the Charlson Index, the Gait Rating Scale,
social risk, quality of life and prevalent chronic diseases were collected.
Results
CKD prevalence was 56.7% for eGFR<60 ml/min/1.73 m2, 19.9% for eGFR<45 ml/min/1.73 m2 and 6.6% for GFR<30 ml/min/1.73 m2. Multiple logistic regression analysis showed that a prior diagnosis of hypertension
was associated with an eGFR<60 ml/min/1.73 m2 (p<0.008, OR 2.134, 95% CI 1.216–3.744). A diagnosis of heart failure (p<0.001, OR 3.610, 95% CI 1.677–7.771) and a poor score on the quality of life measure
(p<0.008, OR 0.9660, 95% CI 0.966–0.995) were associated with an eGFR<45 ml/min/1.73 m2.
Conclusions
More than half of the oldest old in this study had an eGFR<60 ml/min/1.73 m2. A history of hypertension was associated with CKD. The group of patients with an
eGFR<45 ml/min/1.73 m2 was associated with a diagnosis of heart failure and a worse quality of life.
Keywords
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Article info
Publication history
Published online: March 29, 2012
Accepted:
March 7,
2012
Received in revised form:
February 28,
2012
Received:
January 23,
2012
Identification
Copyright
© 2012 European Federation of Internal Medicine. Published by Elsevier Inc. All rights reserved.
