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Depressive symptomatology in patients with metabolic syndrome: A cross-sectional study of stable coronary artery disease patients

Published:August 12, 2015DOI:https://doi.org/10.1016/j.ejim.2015.07.020
      The metabolic syndrome is a common disorder, which includes the presence of at least 3 out of 5 metabolic risk factors according to the National Cholesterol Education Program Adult Treatment Panel III [
      • Grundy S.M.
      • Cleeman J.I.
      • Daniels S.R.
      • Donato K.A.
      • Eckel R.H.
      • Franklin B.A.
      • et al.
      Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement.
      ]. It has been observed that metabolic syndrome is highly prevalent in patients with coronary artery disease (CAD) [
      • Chang J.J.
      • Chu C.M.
      • Wang P.C.
      • Lin Y.S.
      • Pan K.L.
      • Jang S.J.
      • et al.
      Differences in prevalence and severity of coronary artery disease by three metabolic syndrome definitions.
      ] and also depression is a common comorbidity in CAD with an increased risk of cardiovascular morbidity and mortality [
      • Parissis J.T.
      • Fountoulaki K.
      • Filippatos G.
      • Adamopoulos S.
      • Paraskevaidis I.
      • Kremastinos D.
      Depression in coronary artery disease: novel pathophysiologic mechanisms and therapeutic implications.
      ,
      • Rallidis L.S.
      • Varounis C.
      • Sourides V.
      • Charalampopoulos A.
      • Kotakos C.
      • Liakos G.
      • et al.
      Mild depression versus C-reactive protein as a predictor of cardiovascular death: a three year follow-up of patients with stable coronary artery disease.
      ]. The aim of this study was to assess if depressive symptomatology is more prevalent in stable CAD patients with metabolic syndrome.

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