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Letters to the Editor| Volume 30, e17-e18, May 2016

Therapeutic behavior of primary care physicians in patients with atrial fibrillation taking vitamin K antagonists not adequately controlled

Published:January 27, 2016DOI:https://doi.org/10.1016/j.ejim.2016.01.016
Therapeutic behavior of primary care physicians in patients with atrial fibrillation taking vitamin K antagonists not adequately controlled
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      In the majority of patients with atrial fibrillation (AF), long-term oral anticoagulation is necessary to reduce the risk of stroke. Although effective, vitamin K antagonists (VKAs) exhibit many limitations [
      • Camm A.J.
      • Kirchhof P.
      • Lip G.Y.
      • Schotten U.
      • Savelieva I.
      • Ernst S.
      • et al.
      Guidelines for the management of atrial fibrillation: the Task Force for the Management of Atrial Fibrillation of the European Society of Cardiology (ESC).
      Eur Heart J. 2010; 31: 2369-2429
      ,
      • Mearns E.S.
      • White C.M.
      • Kohn C.G.
      • Hawthorne J.
      • Song J.S.
      • Meng J.
      • et al.
      Quality of vitamin K antagonist control and outcomes in atrial fibrillation patients: a meta-analysis and meta-regression.
      Thromb J. 2014; 12: 14
      ]. Despite that, they are still widely used in clinical practice [
      • Lip G.Y.
      • Rushton-Smith S.K.
      • Goldhaber S.Z.
      • Fitzmaurice D.A.
      • Mantovani L.G.
      • Goto S.
      • et al.
      GARFIELD-AF investigators. Does sex affect anticoagulant use for stroke prevention in nonvalvular atrial fibrillation? The prospective global anticoagulant registry in the FIELD-Atrial Fibrillation.
      Circ Cardiovasc Qual Outcomes. 2015; 8: S12-S20
      ].

      Keywords

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      References

        • Camm A.J.
        • Kirchhof P.
        • Lip G.Y.
        • Schotten U.
        • Savelieva I.
        • Ernst S.
        • et al.
        Guidelines for the management of atrial fibrillation: the Task Force for the Management of Atrial Fibrillation of the European Society of Cardiology (ESC).
        Eur Heart J. 2010; 31: 2369-2429
        View in Article
        • Mearns E.S.
        • White C.M.
        • Kohn C.G.
        • Hawthorne J.
        • Song J.S.
        • Meng J.
        • et al.
        Quality of vitamin K antagonist control and outcomes in atrial fibrillation patients: a meta-analysis and meta-regression.
        Thromb J. 2014; 12: 14
        View in Article
        • Lip G.Y.
        • Rushton-Smith S.K.
        • Goldhaber S.Z.
        • Fitzmaurice D.A.
        • Mantovani L.G.
        • Goto S.
        • et al.
        GARFIELD-AF investigators. Does sex affect anticoagulant use for stroke prevention in nonvalvular atrial fibrillation? The prospective global anticoagulant registry in the FIELD-Atrial Fibrillation.
        Circ Cardiovasc Qual Outcomes. 2015; 8: S12-S20
        View in Article
        • Pokorney S.D.
        • Simon D.N.
        • Thomas L.
        • Fonarow G.C.
        • Kowey P.R.
        • Chang P.
        • et al.
        Patients' time in therapeutic range on warfarin among US patients with atrial fibrillation: results from ORBIT-AF registry.
        Am Heart J. 2015; 170: 141-148
        View in Article
        • Barrios V.
        • Escobar C.
        • Prieto L.
        • Osorio G.
        • Polo J.
        • Lobos J.M.
        • et al.
        Anticoagulation control in patients with nonvalvular atrial fibrillation attended at primary care centers in Spain: the PAULA study.
        Rev Esp Cardiol. 2015; 68: 769-776
        View in Article
        • Roldán V.
        • Cancio S.
        • Gálvez J.
        • Valdés M.
        • Vicente V.
        • Marín F.
        • et al.
        The SAMe-TT2R2 score predicts poor anticoagulation control in AF patients: a prospective “real-world” inception cohort study.
        Am J Med. 2015; 128: 1237-1243
        View in Article
        • Nelson W.W.
        • Desai S.
        • Damaraju C.V.
        • Lu L.
        • Fields L.E.
        • Wildgoose P.
        • et al.
        International normalized ratio stabilization in newly initiated warfarin patients with nonvalvular atrial fibrillation.
        Curr Med Res Opin. 2014; 30: 2437-2442
        View in Article
        • Oldenburg J.
        • Müller C.R.
        • Rost S.
        • Watzka M.
        • Bevans C.G.
        Comparative genetics of warfarin resistance.
        Hamostaseologie. 2014; 34: 143-159
        View in Article
        • Bahri O.
        • Roca F.
        • Lechani T.
        • Druesne L.
        • Jouanny P.
        • Serot J.M.
        • et al.
        Underuse of oral anticoagulation for individuals with atrial fibrillation in a nursing home setting in France: comparisons of resident characteristics and physician attitude.
        J Am Geriatr Soc. 2015; 63: 71-76
        View in Article
        • Escobar C.
        • Barrios V.
        • Alonso-Moreno F.J.
        • Prieto M.A.
        • Valls F.
        • Calderon A.
        • et al.
        Evolution of therapy inertia in primary care setting in Spain during 2002–2010.
        J Hypertens. 2014; 32: 1138-1145
        View in Article

      Article info

      Publication history

      Published online: January 27, 2016
      Accepted: January 20, 2016
      Received: January 11, 2016

      Identification

      DOI: https://doi.org/10.1016/j.ejim.2016.01.016

      Copyright

      © 2016 European Federation of Internal Medicine. Published by Elsevier B.V. All rights reserved.

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