- •Homozygotes studied had higher VTE prevalence and modestly lower VTE-free survival.
- •VTE penetrance and phenotype severity, however, did not differ between both genotypes.
- •Our findings suggest VTE management should not differ by Factor V Leiden genotype.
Materials and methods
Abbreviations:APC (Activated protein C), FVa (Factor FVa), PCR (Polymerase chain reaction), PE (Pulmonary embolism), VTE (Venous thromboembolism)
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