Endoscopic retrograde cholangiopancreatography (ERCP) is an uncomfortable procedure
that requires adequate sedation or general anesthesia for successful completion. For
instance, over 48,000 procedures are carried out per annum in the UK alone [
1
,
2
,
3
,
4
]. We performed a prospective review of our hospital's ERCP records, to identify 660
subjects who required propofol. At our institution, propofol sedation for ERCP procedures
is administered by anesthesiologists. The control group consisted of 330 patients
that were not treated using anesthesia because of fear of anesthesia or because they
were urgent cases. In all cases, written consent was necessary, as an acceptance to
perform endoscopic intervention in procedural sedation and analgesia under ambulatory
conditions. Instructions were given in written form. During the endoscopic procedure,
basic monitoring was routinely used: ECG, heart frequency, non-invasive blood pressure
measurement, pulse oximetry, capnometry, respiratory rate and the computer-generated
BIS ranging from 0 (coma) to 100 (fully awake) reflects the level of sedation regardless
of the patient's demographics and the type of hypnotic drug used. After the performed
procedure, patients filed out an individual list of satisfaction degree, by encircling
numbers 1–10 (unsatisfied–satisfied).Keywords
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References
- Safe anaesthesia for ERCP.Anaesthesia. 2011; 66: 395-396
- Petition denial for request for removal of warning of labeling for Diprivan (propofol).in: Docket no FDA-2005-P-0059. August 2010
- Guidance for the use of propofol sedation for adult patients undergoing endoscopic retrograde cholangiopancreatography (ERCP) and other complex upper GI endoscopic procedures.April 2011
- Efficacy of bispectral index monitoring as an adjunct to propofol deep sedation for ERCP: a randomized controlled trial.Endoscopy. 2009; 41: 1046-1051
- Propofol in anesthesia: mechanism of action, structure–activity relationships, and drug delivery.Curr Med Chem. 2007; 7: 249-271
Article info
Publication history
Published online: March 22, 2016
Accepted:
March 1,
2016
Received:
February 28,
2016
Identification
Copyright
© 2016 European Federation of Internal Medicine. Published by Elsevier B.V. All rights reserved.
