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Frailty: The pleasure and pain of geriatric medicine

Published:April 07, 2016DOI:https://doi.org/10.1016/j.ejim.2016.03.018
      Frailty is a geriatric condition characterized by increased vulnerability, resulting from aging-associated declines in reserves and function across multiple physiologic systems, such that the ability to cope with everyday or acute stressors and to maintain organ systems' homeostasis is comprised. Frailty is associated with both negative health outcomes and with increased resource use and for this reason its assessment and treatment are considered to be an essential step to improving the efficiency of healthcare systems. The identification of older adults who are frail, their assessment and the implementation of specific interventions to target frailty represent a cornerstone of geriatric medicine. Despite the fact that the recognition of frailty is increasing in geriatric settings, several gaps still exist that prevent the translation of the theoretical concept of frailty into practice.

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      References

        • Dent E.
        • Kowal P.
        • Hoogendijk E.O.
        Frailty measurement in research and clinical practice: a review.
        Eur J Intern Med. June 2016; 31: 3-10
        • Theou O.
        • Cann L.
        • Blodgett J.
        • Wallace L.M.
        • Brothers T.D.
        • Rockwood K.
        Modifications to the frailty phenotype criteria: systematic review of the current literature and investigation of 262 frailty phenotypes in the survey of health, ageing, and retirement in Europe.
        Ageing Res Rev. May 2015; 21: 78-94
        • Tavassoli N.
        • Guyonnet S.
        • Abellan Van Kan G.
        • Sourdet S.
        • Krams T.
        • Soto M.E.
        • et al.
        Geriatric Frailty Clinic (G.F.C) for assessment of frailty and Prevention of Disability Team. Description of 1,108 older patients referred by their physician to the “Geriatric Frailty Clinic (G.F.C) for assessment of frailty and Prevention of Disability” at the gerontopole.
        J Nutr Health Aging. May 2014; 18: 457-464
        • Cesari M.
        • Marzetti E.
        • Thiem U.
        • Perez Zepeda M.U.
        • Abellan Van Kan G.
        • Landi F.
        • et al.
        The geriatric management of frailty as paradigm of “the end of the disease era”.
        Eur J Intern Med. June 2016; 31: 11-14
        • Cerreta F.
        • Eichler H.G.
        • Rasi G.
        Drug policy for an aging population—the European medicines agency's geriatric medicines strategy.
        N Engl J Med. 2012 Nov 22; 367: 1972-1974
        • Marzetti E.
        • Calvani R.
        • Landi F.
        • Hoogendijk E.O.
        • Fougère B.
        • Vellas B.
        • et al.
        Innovative medicines initiative: the SPRINTT project.
        J Frailty Aging. 2015 Dec 1; 4: 207-208