Cardiovascular diseases are major public health problems. ß-blockers therapy is indicated
for the majority of patients with heart failure and coronary artery disease (Class
I, Level of Evidence: A). These drugs are also first-line therapy for atrial fibrillation.
However, ß-blocker use continues to be less than optimal, principally in patients
with concomitant chronic obstructive lung diseases, such as asthma and chronic obstructive
pulmonary disease (COPD).
Keywords
To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to European Journal of Internal MedicineAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
References
- Adverse respiratory effect of acute beta-blocker exposure in asthma: a systematic review and meta-analysis of randomized controlled trials.Chest. 2014; 145: 779-786
- Cardioselective beta-blockers for chronic obstructive pulmonary disease.Cochrane Database Syst Rev. 2005; CD003566
- Cardioselective beta-blockers in patients with reactive airway disease: a meta-analysis.Ann Intern Med. 2002; 137: 715-725
- The safety and effects of the beta-blocker, nadolol, in mild asthma: an open-label pilot study.Pulm Pharmacol Ther. 2008; 21: 134-141
- Effect of beta blockers in treatment of chronic obstructive pulmonary disease: a retrospective cohort study.BMJ. 2011; 342: d2549
- Beta-blockers reduced the risk of mortality and exacerbation in patients with COPD: a meta-analysis of observational studies.PLoS One. 2014; 9e113048
- Beta blockers for asthma: a double-edged sword.Lancet. 2009; 373: 104-105
- Randomized placebo-controlled trial to evaluate chronic dosing effects of propranolol in asthma.Am J Respir Crit Care Med. 2013; 187: 1308-1314
- The intrinsic bias of generalizations.Am J Respir Crit Care Med. 2014; 189: 359
- New perspectives regarding beta(2)-adrenoceptor ligands in the treatment of asthma.Br J Pharmacol. 2011; 163: 18-28
Article info
Publication history
Published online: May 11, 2016
Accepted:
April 27,
2016
Received:
April 20,
2016
Footnotes
☆The authors declare no conflicts of interest related to this study.
Identification
Copyright
© 2016 European Federation of Internal Medicine. Published by Elsevier B.V. All rights reserved.