Thromboprophylaxis for patients with coronary artery disease and atrial fibrillation
(AF) is problematic when there is a low or moderate risk of stroke (CHADS2 score = 0 or 1), particularly when patients experience an acute coronary syndrome or undergo
intracoronary stent implantation. Some physicians may be reluctant to prescribe oral
anticoagulation (OAC) in these patients and several recent guidelines propose slightly
different management in such settings [
1
,
2
]. Our goal was to evaluate whether treatment with an OAC is appreciably beneficial
in these AF patients.- Lip G.Y.H.
- Windecker S.
- Huber K.
- Kirchhof P.
- Marin F.
- Ten Berg J.M.
- et al.
Management of antithrombotic therapy in atrial fibrillation patients presenting with
acute coronary syndrome and/or undergoing percutaneous coronary or valve interventions:
a joint consensus document of the European Society of Cardiology Working Group on
thrombosis, European Heart Rhythm Association (EHRA), European Association of Percutaneous
Cardiovascular Interventions (EAPCI) and European Association of Acute Cardiac Care
(ACCA) endorsed by the Heart Rhythm Society (HRS) and Asia-Pacific Heart Rhythm Society
(APHRS).
Eur Heart J. 2014; 35: 3155-3179
Keywords
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References
- Guidelines for the management of atrial fibrillation: the Task Force for the Management of Atrial Fibrillation of the European Society of Cardiology (ESC).Eur Heart J. 2010; 31: 2369-2429
- Management of antithrombotic therapy in atrial fibrillation patients presenting with acute coronary syndrome and/or undergoing percutaneous coronary or valve interventions: a joint consensus document of the European Society of Cardiology Working Group on thrombosis, European Heart Rhythm Association (EHRA), European Association of Percutaneous Cardiovascular Interventions (EAPCI) and European Association of Acute Cardiac Care (ACCA) endorsed by the Heart Rhythm Society (HRS) and Asia-Pacific Heart Rhythm Society (APHRS).Eur Heart J. 2014; 35: 3155-3179
- Should we recommend oral anticoagulation therapy in patients with atrial fibrillation undergoing coronary artery stenting with a high HAS-BLED bleeding risk score?.Circ Cardiovasc Interv. 2012; 5: 459-466
- Comparison of different antithrombotic regimens for patients with atrial fibrillation undergoing drug-eluting stent implantation.Circ J. 2010; 74: 701-708
- The optimal management of patients on oral anticoagulation undergoing coronary artery stenting. The 10th Anniversary Overview.Thromb Haemost. 2014; 112: 1080-1087
- Use of clopidogrel with or without aspirin in patients taking oral anticoagulant therapy and undergoing percutaneous coronary intervention: an open-label, randomised, controlled trial.Lancet. 2013; 381: 1107-1115
Article info
Publication history
Published online: August 27, 2016
Accepted:
August 16,
2016
Received:
August 10,
2016
Identification
Copyright
© 2016 European Federation of Internal Medicine. Published by Elsevier B.V. All rights reserved.