With variable and nonspecific clinical manifestations [
[1]
], pulmonary embolism (PE) is associated with a mortality of approximately 30% and
may cause sudden death within a few hours [
[2]
]. Therefore, diagnosis is challenging for clinicians as only 10–15% of patients underwent
computer tomography pulmonary angiography (CTPA) were actually diagnosed as having
the condition, which unavoidably leads to unnecessary and expensive investigations
and adds their associated risks. Contrarily, in many rural hospitals of China, the
CTPA cannot be performed for patients with suspected PE because of the lack of devices.Keywords
To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to European Journal of Internal MedicineAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
References
- Eur Heart J. 2014; 35: 3033-3073
- Comparison of wells and revised Geneva rule to assess pretest probability of pulmonary embolism in high-risk hospitalized elderly adults.J Am Geriatr Soc. 2015; 63: 1091-1097
- Comparison of the wells score with the simplified revised Geneva score for assessing pretest probability of pulmonary embolism.Thromb Res. 2011; 127: 81-84
- Derivation of a simple clinical model to categorize patients probability of pulmonary embolism: increasing the models utility with the SimpliRED D-dimer.Thromb Haemost. 2000; 83: 416-420
- Diagnosis and management of pulmonary embolism in the elderly.Eur J Intern Med. 2014; 25: 343-349
- Safety of withholding anticoagulant therapy in patients with suspected pulmonary embolism with a negative multislice computed tomography pulmonary angiography.Eur J Intern Med. 2010; 21: 283-288
- Performance of 4 clinical decision rules in the diagnostic management of acute pulmonary embolism: a prospective cohort study.Ann Intern Med. 2011; 154: 709-718
- Alternative diagnosis other than pulmonary embolism as a subjective variable in the wells clinical decision rule: not so bad after all.J Thromb Haemost. 2007; 5: 1079-1080
- Comparison of the wells and revised Geneva scores for the diagnosis of pulmonary embolism: an Australian experience.Intern Med J. 2011; 41: 258-263
- Age-adjusted D-dimer cutoff levels to rule out pulmonary embolism: the ADJUST-PE study.JAMA. 2014; 311: 1117-1124
Article info
Publication history
Published online: September 17, 2016
Accepted:
September 7,
2016
Received in revised form:
September 7,
2016
Received:
July 27,
2016
Footnotes
☆Financial support: Cangzhou Science and Technology Research and Development Program (cz1213056ZD).
Identification
Copyright
© 2016 European Federation of Internal Medicine. Published by Elsevier B.V. All rights reserved.