Advertisement

Acute effect of dark chocolate on red blood cell distribution width

Published:September 30, 2016DOI:https://doi.org/10.1016/j.ejim.2016.09.015
      Evidence accumulated over the past decades attests that moderate consumption of chocolate, especially dark chocolate, may produce favorable effects against cardiovascular disease [
      • Lippi G.
      • Franchini M.
      • Montagnana M.
      • Favaloro E.J.
      • Guidi G.C.
      • Targher G.
      Dark chocolate: consumption for pleasure or therapy?.
      ]. Since anisocytosis, conventionally reflected by the amplitude of the red blood cell (RBC) distribution width (RDW), is increasingly regarded as a reliable marker and predictor of many cardiovascular disorders [
      • Danese E.
      • Lippi G.
      • Montagnana M.
      Red blood cell distribution width and cardiovascular diseases.
      ], we planned an original study to assess the impact of acute intake of dark chocolate on RDW.

      Keywords

      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to European Journal of Internal Medicine
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • Lippi G.
        • Franchini M.
        • Montagnana M.
        • Favaloro E.J.
        • Guidi G.C.
        • Targher G.
        Dark chocolate: consumption for pleasure or therapy?.
        J Thromb Thrombolysis. 2009; 28: 482-488
        • Danese E.
        • Lippi G.
        • Montagnana M.
        Red blood cell distribution width and cardiovascular diseases.
        J Thorac Dis. 2015; 7: E402-E411
        • Lippi G.
        • Filippozzi L.
        • Montagnana M.
        • Salvagno G.L.
        • Franchini M.
        • Guidi G.C.
        • et al.
        Clinical usefulness of measuring red blood cell distribution width on admission in patients with acute coronary syndromes.
        Clin Chem Lab Med. 2009; 47: 353-357
        • Söderholm M.
        • Borné Y.
        • Hedblad B.
        • Persson M.
        • Engström G.
        Red cell distribution width in relation to incidence of stroke and carotid atherosclerosis: a population-based cohort study.
        PLoS One. 2015; 10e0124957
        • Lippi G.
        • Buonocore R.
        • Cervellin G.
        Value of red blood cell distribution width on emergency department admission in patients with venous thrombosis.
        Am J Cardiol. 2016; 117: 670-675
        • Lippi G.
        • Targher G.
        • Salvagno G.L.
        • Guidi G.C.
        Increased red blood cell distribution width (RDW) is associated with higher glycosylated hemoglobin (HbA1c) in the elderly.
        Clin Lab. 2014; 60: 2095-2098