High blood pressure (BP) is an important factor causing acute decompensated heart
failure (HF). An abrupt increase in BP has been associated with a surge in neurohormonal
and cytokine activation, which is one of the triggers of acute decompensated HF and
reported to induce redistribution of fluids from the systemic to pulmonary circulation,
further neurohormonal activation, and increased left ventricular (LV) afterload [
[1]
]. On the other hand, long-standing hypertension leads to structural remodeling of
the heart [
2
,
3
]. Although determinants of the LV functional and structural response to hypertension
and interindividual variability thereof remain ill-defined [
[2]
], patients with hypertensive HF (HTNHF) may show certain clinical characteristics
that are distinct from those in patients with non-hypertensive HF (nonHTNHF), and
the underlying pathophysiology can differ between these patient groups. Assessing
the clinical characteristics and mechanisms of HTNHF is thus an important research
topic from the viewpoint of individualized medicine. Accordingly, we compared the
prognostic factors for one-year mortality between patients with hypertensive and non-hypertensive
acute decompensated HF in the present study.Keywords
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Article info
Publication history
Published online: November 02, 2016
Accepted:
October 25,
2016
Received:
October 19,
2016
Identification
Copyright
© 2016 European Federation of Internal Medicine. Published by Elsevier B.V. All rights reserved.
