The six-minute walk test (6MWT) and cardiopulmonary exercise testing (CPET) are two
objective modalities utilized for examining the functional status in patients with
heart failure (HF). CPET reproducibly determines maximum exercise capacity through
measurements of peak oxygen uptake (peak VO2) and other ventilatory variables, and
was shown to provide additional prognostic information that prioritize patients for
heart transplantation (HT) and mechanical circulatory support, and predicts mortality
[
[1]
]. The 6MWT is used as an alternative to CPET to evaluate the functional capacity in
HF because of ease of its implementation and good tolerability, and has thus been
considered a submaximal exercise test [
2
,
3
]. Prior studies demonstrated the relationship between 6MWT and peak VO2 in HF [
2
,
4
]. We aim to investigate the longitudinal relationship between distance walked (6MWD)
and CPET-derived variables in patients with acute systolic HF, and to examine the
association between HF symptoms and both tests.Keywords
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References
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Article info
Publication history
Published online: January 05, 2017
Accepted:
December 16,
2016
Received:
December 13,
2016
Footnotes
☆No funding has been received for this manuscript.
Identification
Copyright
© 2016 European Federation of Internal Medicine. Published by Elsevier B.V. All rights reserved.