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The association between a simple measure of QRS voltage and the in-hospital mortality of acutely ill medical patients

Published:March 07, 2017DOI:https://doi.org/10.1016/j.ejim.2017.03.001
      There are multiple causes of low QRS voltage on the ECG, and often it is unexplained and considered to be a normal variant [
      • Madias J.E.
      Low QRS voltage and its causes.
      ], occurring in 1.4% of individuals free of cardiovascular disease [
      • Usoro A.O.
      • Bradford N.
      • Shah A.J.
      • Soliman E.Z.
      Risk of mortality in individuals with low QRS voltage and free of cardiovascular disease.
      ]. Although recently low QRS voltage has been shown to be associated with increased mortality in the general population [
      • Usoro A.O.
      • Bradford N.
      • Shah A.J.
      • Soliman E.Z.
      Risk of mortality in individuals with low QRS voltage and free of cardiovascular disease.
      ], as far as we know a relationship between low QRS voltage and the in-hospital mortality of acutely ill patients has never been reported. Recently a good correlation has been reported between weight loss in patients with heart failure and the combined amplitudes of the QRS complexes of ECG lead I and II [
      • Lumlertgul S.
      • Chenthanakij B.
      • Madias J.E.
      ECG leads I and II to evaluate diuresis of patients with congestive heart failure admitted to the hospital via the emergency department.
      ]. This prompted us to explore if this simple measure also had any prognostic value for acutely ill medical patients.

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