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Differences in short and long-term survival between males and females with new-onset heart failure: A retrospective cohort study

Published:March 20, 2017DOI:https://doi.org/10.1016/j.ejim.2017.03.010
      A meta-analysis of 31 studies (MAGGIC) [
      • Pocock S.J.
      • Ariti C.A.
      • McMurray J.J.
      • et al.
      Predicting survival in heart failure: a risk score based on 39 372 patients from 30 studies.
      ] has shown that women with heart failure (HF) have better survival than men. However, these studies were limited by selective patient populations (e.g. randomized controlled trials, hospital-based cohorts), relatively small study samples (N ≤ 500), or short follow-up. Other analyses of the MAGICC data indicated that in HF patients of ischemic etiology [
      • Ghali J.K.
      • Krause-Steinrauf H.J.
      • Adams K.F.
      • et al.
      Gender differences in advanced heart failure: insights from the BEST study.
      ,
      • Martínez-Sellés M.
      • Doughty R.N.
      • Poppe K.
      • et al.
      Gender and survival in patients with heart failure: interactions with diabetes and aetiology. Results from the MAGGIC individual patient meta-analysis.
      ] or concomitant diabetes mellitus (DM) [
      • Martínez-Sellés M.
      • Doughty R.N.
      • Poppe K.
      • et al.
      Gender and survival in patients with heart failure: interactions with diabetes and aetiology. Results from the MAGGIC individual patient meta-analysis.
      ], differences in survival between sexes are largely attenuated. In this population-based, retrospective cohort study we assess long-term survival of men and women with HF.

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      References

        • Pocock S.J.
        • Ariti C.A.
        • McMurray J.J.
        • et al.
        Predicting survival in heart failure: a risk score based on 39 372 patients from 30 studies.
        Eur Heart J. 2013; 34: 1404-1413
        • Ghali J.K.
        • Krause-Steinrauf H.J.
        • Adams K.F.
        • et al.
        Gender differences in advanced heart failure: insights from the BEST study.
        J Am Coll Cardiol. 2003; 42: 2128-2134
        • Martínez-Sellés M.
        • Doughty R.N.
        • Poppe K.
        • et al.
        Gender and survival in patients with heart failure: interactions with diabetes and aetiology. Results from the MAGGIC individual patient meta-analysis.
        Eur J Heart Fail. 2012; 14: 473-479
        • Felker G.M.
        • Lee K.L.
        • Bull D.A.
        • et al.
        Diuretic strategies in patients with acute decompensated heart failure.
        N Engl J Med. 2011; 364: 797-805
        • Therneau T.
        A package for survival analysis in S. Version 2.38.
        2015
        • Roger V.L.
        Epidemiology of heart failure.
        Circ Res. 2013; 113: 646-659
        • Erez A.
        • Klempfner R.
        • Goldenberg I.
        • et al.
        Short and long term survival following hospitalization with a primary versus non-primary diagnosis of acute heart failure.
        Eur J Intern Med. 2015; 26: 420-424
        • Berry C.
        • Doughty R.N.
        • Granger C.
        • et al.
        The survival of patients with heart failure with preserved or reduced left ventricular ejection fraction: an individual patient data meta-analysis.
        Eur Heart J. 2011; 33: 1750-1757
        • Klempfner R.
        • Koifman E.
        • Goldenberg I.
        • et al.
        The Israel nationwide heart failure survey: sex differences in early and late mortality for hospitalized heart failure patients.
        J Card Fail. 2014; 20: 193-198
        • Gotsman I.
        • Zwas D.
        • Zemora Z.
        • et al.
        Clinical outcome of patients with chronic heart failure followed in a specialized heart failure center.
        Isr Med Assoc J. 2011; 13: 468-473