Highlights
- •The effect of periodontal treatment in asthma control remains unclear.
- •Asthmatics underwent periodontal treatment were at lower risk of hospitalization for adverse respiratory events.
- •Periodontal treatment group had lower intensive care demands for these events.
- •All-cause mortality was also significantly lower in the periodontal treatment group.
Abstract
Background
Periodontal disease is prevalent in asthmatics, but it is unclear whether periodontal
treatment plays a role in adverse respiratory events in these patients. We evaluated
risk of hospitalization for adverse respiratory events (acute exacerbation, pneumonia,
and acute respiratory failure) and mortality in asthmatic adults with and without
periodontal treatment.
Methods
We used National Health Insurance (NHI) claims data of Taiwan to identify 4771 asthmatic
adults with periodontal disease who underwent periodontal treatment during 2000–2006.
The control group consisted of asthmatic adults without periodontal disease at a 1:1
ratio matched by the propensity score. Both groups were followed up for 5 years to estimate the risk of hospitalization for adverse respiratory events and mortality.
Results
Compared with controls, the periodontal treatment group had lower overall incidence
of hospitalization for adverse respiratory events [5.41 vs. 6.07 per 100 person-years,
95% confidence interval (CI) = 0.78–0.92] and intensive care unit admissions (1.14 vs. 1.25 per 100 person-years,
95% CI = 0.79–0.99). In addition, the all-cause mortality rate was significantly lower in the
periodontal treatment group than in the control group during the follow-up period
(1.86 vs. 2.79 per 100 person-years, 95% CI = 0.59–0.71).
Conclusion
Asthmatic adults who underwent periodontal treatment were at lower risk of hospitalization
for adverse respiratory events and mortality than those without periodontal disease.
Asthmatic adults should adopt more precautionary oral hygiene and ensure that they
undergo regular periodontal health checkups.
Keywords
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Article info
Publication history
Published online: June 07, 2017
Accepted:
June 5,
2017
Received in revised form:
June 2,
2017
Received:
March 14,
2017
Identification
Copyright
© 2017 European Federation of Internal Medicine. Published by Elsevier B.V. All rights reserved.
