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Eye problem in Zika virus infection

      The recent publication on Zika virus infection is very interesting [
      • Bandyopadhyay D.
      • Hajra A.
      ZIKA virus: a new threat to the eyes.
      ]. As noted by Bandyopadhyay and Hajra, there are several possible eye problems due to Zika virus infection [
      • Bandyopadhyay D.
      • Hajra A.
      ZIKA virus: a new threat to the eyes.
      ]. An important concern is the hidden eye problem in cases with Zika virus infection. Bandyopadhyay and Hajra might focus on the eye problems seen in the infants with Zika virus infection but the problem in adult cases should not be forgotten. In fact, most cases with Zika virus infection are asymptomatic [
      • Wiwanitkit S.
      • Wiwanitkit V.
      Afebrile, asymptomatic and non-thrombocytopenic Zika virus infection: don't miss it!.
      ]. Nevertheless, the main question is whether there is any underdiagnosed eye problem in those asymptomatic cases. The eye examination is usually not a recommendation in evaluation the cases with Zika virus infection. It is the time to consider the eye examination in clinical examination on any cases with suspicious Zika virus infection [
      • Wiwanitkit V.
      Ocular finding in Zika virus infection response letter: serological evidence confirms the presumed diagnosis of Zika virus congenital infection in infants with microcephaly and ocular findings. Zika virus outbreak in the Americas: the need for novel mosquito control methods. The Brazilian Zika virus strain causes birth defects in experimental models. Ophthalmologic findings in infants with microcephaly and presumable intra-uterus Zika virus infection. Zika virus in Brazil and macular atrophy in a child with microcephaly. Variables related to the ophthalmoscopic findings identified in infants with presumed Zika virus congenital infection.
      ].

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      References

        • Bandyopadhyay D.
        • Hajra A.
        ZIKA virus: a new threat to the eyes.
        Eur J Intern Med. 2017; 44: e9-e10
        • Wiwanitkit S.
        • Wiwanitkit V.
        Afebrile, asymptomatic and non-thrombocytopenic Zika virus infection: don't miss it!.
        Asian Pac J Trop Med. May 2016; 9: 513
        • Wiwanitkit V.
        Ocular finding in Zika virus infection response letter: serological evidence confirms the presumed diagnosis of Zika virus congenital infection in infants with microcephaly and ocular findings. Zika virus outbreak in the Americas: the need for novel mosquito control methods. The Brazilian Zika virus strain causes birth defects in experimental models. Ophthalmologic findings in infants with microcephaly and presumable intra-uterus Zika virus infection. Zika virus in Brazil and macular atrophy in a child with microcephaly. Variables related to the ophthalmoscopic findings identified in infants with presumed Zika virus congenital infection.
        Arq Bras Oftalmol. Jul–Aug 2016; 79: 280