Highlights
- •A national sample was employed.
- •An objective measure of physical activity was utilized.
- •Non-bouted physical activity was associated with reduced retinopathy prevalence.
Abstract
Objective
We evaluated the specific differential association between non-bouted, lifestyle physical
activities (vs. structured exercise; i.e., bouted physical activity) on retinopathy
prevalence among a national sample of the broader U.S. adult population.
Methods
Data from the 2005–2006 National Health and Nutrition Examination Survey (NHANES)
was used to identify 1501 adults, between 40 and 85 years. Bouted and non-bouted physical activities were assessed using objective accelerometer
monitoring. A 10-minute bout was defined as 10+ consecutive minutes above the moderate-to-vigorous physical activity (MVPA) cut-point,
with the allowance of 1–2-minute interruption intervals. Non-bout MVPA was determined
by the number of MVPA minutes not accrued in a bout. Participants were screened for
non-proliferative retinopathy using Early Treatment Diabetic Retinopathy Study grading
criteria, as well as objective retinal imaging assessments using the Canon Non-Mydriatic
Retinal Camera CR6-45NM. Individuals were excluded if they had been diagnosed with
coronary artery disease, congestive heart failure, heart attack or stroke.
Results
Participants with worse retinopathy engaged in less bouted and non-bouted physical
activity, had a higher BMI and were more likely to have diabetes and hypertension.
For every 1 min/day increase in non-bouted MVPA, participants had a 7% reduced odds of moderate-to-severe
retinopathy compared to no retinopathy (OR = 0.93; 95% CI: 0.87–0.99; P = 0.04); results were similar in an unadjusted model (OR = 0.93; 95% CI: 0.89–0.97; P = 0.007). Bouted MVPA was not associated with retinopathy prevalence in the multivariate
model.
Conclusion
In this nationally representative sample of adults, those who engaged in non-bouted
physical activity had reduced odds of a diagnosis of moderate-to-severe retinopathy.
Keywords
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Article info
Publication history
Published online: August 14, 2017
Accepted:
August 12,
2017
Received in revised form:
June 26,
2017
Received:
May 22,
2017
Identification
Copyright
© 2017 European Federation of Internal Medicine. Published by Elsevier B.V. All rights reserved.
