Immune thrombocytopenia (ITP) is the most common autoimmune cytopenia. This disease
often occurs in young women [
[1]
]. Pregnancy is a well-known risk factor for developing newly diagnosed ITP as well
as for inducing disease flares in patients with chronic ITP [
[2]
]. Severe bleeding is rare but a therapeutic intervention is needed for one third of
the pregnant patients, mostly before delivery to allow peridural analgesia [
3
,
4
]. However, the impact of pregnancy in women with an old history of ITP, considered
as cured, has not been assessed. The aim of this study was to describe the course
of ITP in pregnant women with an ITP in complete remission (platelet count > 100 × 109/L and absence of bleeding symptoms) for at least 5 years without any ITP treatment.Keywords
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References
- Epidemiology of incident immune thrombocytopenia: a nationwide population-based study in France.Blood. 2014; 124: 3308-3315https://doi.org/10.1182/blood-2014-05-578336
- Idiopathic thrombocytopenic purpura complicating pregnancy.Blood Rev. 2002; 16: 43-46https://doi.org/10.1054/blre.2001.0181
- Effect of pregnancy on the course of immune thrombocytopenia: a retrospective study of 118 pregnancies in 82 women.Br J Haematol. 2014; 166: 929-935https://doi.org/10.1111/bjh.12976
- A retrospective 11-year analysis of obstetric patients with idiopathic thrombocytopenic purpura.Blood. 2003; 102: 4306-4311https://doi.org/10.1182/blood-2002-10-3317
- Validation of immune thrombocytopenia diagnosis code in the French hospital electronic database.Eur J Intern Med. 2016; 32: e21-22https://doi.org/10.1016/j.ejim.2016.02.021
- The American Society of Hematology 2011 evidence-based practice guideline for immune thrombocytopenia.Blood. 2011; 117: 4190-4207https://doi.org/10.1182/blood-2010-08-302984
- Standardization of terminology, definitions and outcome criteria in immune thrombocytopenic purpura of adults and children: report from an international working group.Blood. 2009; 113: 2386-2393https://doi.org/10.1182/blood-2008-07-162503
- How I treat thrombocytopenia in pregnancy.Blood. 2013; 121: 38-47https://doi.org/10.1182/blood-2012-08-448944
- Standardization of bleeding assessment in immune thrombocytopenia: report from the International Working Group.Blood. 2013; 121: 2596-2606https://doi.org/10.1182/blood-2012-07-442392
Article info
Publication history
Published online: August 26, 2017
Accepted:
August 22,
2017
Received in revised form:
August 21,
2017
Received:
August 14,
2017
Identification
Copyright
© 2017 European Federation of Internal Medicine. Published by Elsevier B.V. All rights reserved.
