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When subclinical hypothyroidism becomes clinically diagnosed

Published:September 29, 2017DOI:https://doi.org/10.1016/j.ejim.2017.09.034
      Lili Ilse Elvenes (*1882 Denmark–†1931 Germany) was one of the first transgender women who ultimately died from on a series of risky and essentially unproven operations to remove her male parts and transplant female reproductive organs. Her remarkable life history – made into ‘The Danish Girl’ and the learnings thereof – carries important messages about how we, citizens and doctors alike, should deal with hormonal conditions. There are instructive parallels with other disorders, for example, insufficiency of the thyroid gland. The Danish girls and boys of today, who suffer hypothyroidism, have a similar mix of signs and symptoms, intended- and unintended effects of treatment, and placebo- and nocebo-effects, thus posing us with an emergent socio-, and medical challenge.

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