We would like to thank Dr. Davide Giuseppe Ribaldone and colleagues for their interest
in our article “The contribution of clinical and pathological predisposing factors
to severe gastro-duodenal lesions in patients with long-term low-dose aspirin and
proton pump inhibitor therapy” [
[1]
].They raised the problem of possible false negative diagnosis of Helicobacter pylori (H. pylori) infection using biopsy in patients with ongoing treatment with proton pump inhibitors
(PPI) and offer us the opportunity to clarify some methodological aspects. They also
discussed the possibility of cessation of PPI before endoscopy and the evaluation
of antibodies to H. pylori in serum as a confirmatory test of infection, which allow us to comment certain local
aspects of this issue.Keywords
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References
- The contribution of clinical and pathological predisposing factors to severe gastro-duodenal lesions in patients with long-term low-dose aspirin and proton pump inhibitor therapy.Eur J Intern Med. 2017; 44: 62-66
- American College of Cardiology Foundation Task Force on clinical expert consensus documents. ACCF/ACG/AHA 2008 expert consensus document on reducing the gastrointestinal risks of antiplatelet therapy and NSAID use: a report of the American College of Cardiology Foundation Task Force on clinical expert consensus documents.Circulation. 2008; 118 (28): 1894-1909
- Management of Helicobacter pylori infection—the Maastricht V/Florence consensus report.Gut. 2017; 66: 6-30
- Gastritis: the histology report.Dig Liver Dis. 2011; 43: S373-84
- The stomach in health and disease.Gut. 2015; 64: 1650-1668
- Changes in Helicobacter pylori-induced gastritis in the antrum and corpus during 12 months of treatment with omeprazole and lansoprazole in patients with gastro-oesophageal reflux disease.Aliment Pharmacol Ther. 1998; 12: 247-253
- Systematic review: the effects of long-term proton pump inhibitor use on serum gastrin levels and gastric histology.Aliment Pharmacol Ther. 2015; 42: 649-663
- Proton-pump inhibitors: understanding the complications and risks.Nat Rev Gastroenterol Hepatol. Sep 20, 2017; https://doi.org/10.1038/nrgastro.2017.117
Article info
Publication history
Published online: December 01, 2017
Accepted:
November 28,
2017
Received:
November 24,
2017
Identification
Copyright
© 2017 European Federation of Internal Medicine. Published by Elsevier B.V. All rights reserved.
