High molecular mass forms have been reported for many serum enzymes measured in clinical
laboratories. They are described as either type-1 (a normal enzyme complexed with
an immunoglobulin by an antigen-antibody reaction) or type-2 macroenzymes (all other).
They are detected in patients examined for persistently increased levels using electrophoretic,
chromatographic or immunoinhibition methods, but are indistinguishable from normal
enzymes in routine quantitative assays [
[1]
].Keywords
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Article info
Publication history
Published online: February 15, 2018
Accepted:
February 5,
2018
Received:
February 2,
2018
Identification
Copyright
© 2018 European Federation of Internal Medicine. Published by Elsevier B.V. All rights reserved.
