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A new standardized data collection system for interdisciplinary thyroid cancer management: Thyroid COBRA

Published:February 21, 2018DOI:https://doi.org/10.1016/j.ejim.2018.02.012

      Highlights

      • Big data approach represents an alternative to EBM for thyroid cancer management.
      • The thyroid COBRA-Storage System (C-SS) is not time-consuming and privacy respecting.
      • The development of the C-SS through a multicentre consortium approach is feasible.
      • The thyroid C-SS can be applied in the near future to every cancer type.

      Abstract

      The big data approach offers a powerful alternative to Evidence-based medicine. This approach could guide cancer management thanks to machine learning application to large-scale data. Aim of the Thyroid CoBRA (Consortium for Brachytherapy Data Analysis) project is to develop a standardized web data collection system, focused on thyroid cancer.
      The Metabolic Radiotherapy Working Group of Italian Association of Radiation Oncology (AIRO) endorsed the implementation of a consortium directed to thyroid cancer management and data collection. The agreement conditions, the ontology of the collected data and the related software services were defined by a multicentre ad hoc working-group (WG).
      Six Italian cancer centres were firstly started the project, defined and signed the Thyroid COBRA consortium agreement. Three data set tiers were identified: Registry, Procedures and Research. The COBRA-Storage System (C-SS) appeared to be not time-consuming and to be privacy respecting, as data can be extracted directly from the single centre's storage platforms through a secured connection that ensures reliable encryption of sensible data. Automatic data archiving could be directly performed from Image Hospital Storage System or the Radiotherapy Treatment Planning Systems.
      The C-SS architecture will allow “Cloud storage way” or “distributed learning” approaches for predictive model definition and further clinical decision support tools development.
      The development of the Thyroid COBRA data Storage System C-SS through a multicentre consortium approach appeared to be a feasible tool in the setup of complex and privacy saving data sharing system oriented to the management of thyroid cancer and in the near future every cancer type.

      Keywords

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