Systemic sclerosis (SSc) is an autoimmune disease characterized by fibrosis of skin
and internal organs, endothelial and microvascular damage. Erectile dysfunction (ED)
is a major issue for male with high prevalence and great impact on quality of life
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References
- The clinical relevance of sexual dysfunction in systemic sclerosis.Autoimmun Rev. 2015; 14: 1111-1115
- Erectile dysfunction is frequent in systemic sclerosis and associated with severe disease: a study of the EULAR Scleroderma Trial and Research group.Arthritis Res Ther. 2012; 14: R37
- Erectile dysfunction in systemic sclerosis.Curr Rheumatol Rep. 2016; 18: 49
- Nailfold capillary abnormalities in erectile dysfunction of systemic sclerosis: a EUSTAR group analysis.Rheumatology. 2014; 53: 639-643
- Erectile dysfunction, endothelium dysfunction, and microvascular damage in patients with systemic sclerosis.J Sex Med. 2013; 10: 1380-1388
- Erectile dysfunction of sclerodermic patients correlates with digital vascular damage.Eur J Intern Med. 2011; 22: 318-321
- Angiogenic and angiostatic factors in systemic sclerosis: increased levels of vascular endothelial growth factor are a feature of the earliest disease stages and are associated with the absence of fingertip ulcers.Arthritis Res. 2002; 4: R11
- Increased concentrations of the circulating angiogenesis inhibitor endostatin in patients with systemic sclerosis.Arthritis Rheum. 2000; 43: 889-893
Article info
Publication history
Published online: April 24, 2018
Accepted:
April 19,
2018
Received:
April 16,
2018
Identification
Copyright
© 2018 European Federation of Internal Medicine. Published by Elsevier B.V. All rights reserved.
