Sepsis is a life-threatening, high-mortality syndrome that is still lacking a validated
standard diagnostic test, although it is widely recognised that early identification
of these conditions is a key factor for improving prognosis. Sepsis and septic shock
are both underdiagnosed and undertreated [
[1]
]. In order to quickly identify septic patients at higher risk of negative outcomes,
several scores have been proposed as valuable screening tools such as SIRS (Systemic
Inflammatory Response Syndrome) [
[2]
], modified Early Warning Score (MEWS) score [
[3]
] and the Sequential [Sepsis-related] Organ Failure Assessment (SOFA) score [
[4]
]. Recently, the quick SOFA (qSOFA) score was proposed as to identify septic patients
who have higher risk of negative outcomes [
- Vincent J.L.
- Moreno R.
- Takala J.
- Willatts S.
- De Mendonça A.
- Bruining H.
- et al.
The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure.
On behalf of the working group on Sepsis-related problems of the European Society
of Intensive Care Medicine.
Intensive Care Med. 1996; 22: 707-710
[5]
]. The advantage of the qSOFA score is being based on three parameter evaluation (respiratory
rate, mental status and blood pressure), without the need of laboratory tests. Aim
of the present study was to evaluate the predictivity of qSOFA compared with other
prognostic scores (SIRS criteria, MEWS score and SOFA score) of in-hospital mortality
and ICU admission in consecutive patients admitted to the local Emergency Department
(ED). The correlation between the BCs results and prognostic scores was also analyzed.Keywords
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References
- Three-hour bundle compliance and outcomes in patients with undiagnosed severe sepsis.Chest. 2018; 153: 39-45
- Influence of systemic inflammatory response syndrome and sepsis on outcome of critically ill infected patients.Am J Respir Crit Care Med. 2003; 168: 77-84
- Validation of a modified early warning score in medical admissions.QJM. 2001; 94: 521-526
- The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure. On behalf of the working group on Sepsis-related problems of the European Society of Intensive Care Medicine.Intensive Care Med. 1996; 22: 707-710
- Assessment of clinical criteria for Sepsis: for the third international consensus definitions for Sepsis and septic shock (Sepsis-3).JAMA. 2016; 315: 762-774
- Performance of the quick sequential (Sepsis-related) organ failure assessment score as a prognostic tool in infected patients outside the intensive care unit: a systematic review and meta-analysis.Crit Care. 2018; 22: 28
- Validation of the qSOFA score for identification of septic patients: a retrospective study.Eur J Intern Med. 2016; 36e35-e36
- Characteristics and outcomes of culture-negative versus culture-positive severe sepsis.Crit Care. 2013; 17: R202
- The role of infection and comorbidity: factors that influence disparities in Sepsis.Crit Care Med. 2006; 34: 2576-2582
Article info
Publication history
Published online: June 04, 2018
Accepted:
May 14,
2018
Received:
May 11,
2018
Identification
Copyright
© 2018 European Federation of Internal Medicine. Published by Elsevier B.V. All rights reserved.
