Highlights
- •More than a half of chronic pain patients are not treated at admission.
- •Almost a half of chronic pain patients are still not treated at discharge.
- •Treated chronic patients do not decrease significantly their pain intensity.
- •It is a needed a greater attention to the management of chronic pain in elderly.
Abstract
Background
Chronic pain is a frequent characteristic of elderly people and represents an actual
and still poorly debated topic.
Objective
We investigated pain prevalence and intensity, and its pharmacological therapy in
elderly patients hospitalized in 101 internal medicine wards.
Methods
Taking advantage of the “REgistro POliterapie Società Italiana Medicina Interna” (REPOSI),
we collected 2535 patients of whom almost a quarter was older than 85 years old. Among
them, 582 patients were affected by pain (either chronic or acute) and 296 were diagnosed
with chronic pain.
Results
Patients with pain showed worse cognitive status, higher depression and comorbidities,
and a longer duration of hospital stay compared to those without pain (all p < .0366). Patients with chronic pain revealed lower level of independency in their
daily life, worse cognitive status and higher level of depression compared to acute
pain patients (all p < .0156). Moreover, most of them were not treated for pain at admission (73.4%) and
half of them was not treated with any analgesic drug at discharge (50.5%). This difference
affected also the reported levels of pain intensity. Patients who received analgesics
at both admission and discharge remained stable (p = .172). Conversely, those not treated at admission who received an analgesic treatment
during the hospital stay decreased their perceived pain (p < .0001).
Conclusions
Our results show the need to focus more attention on the pharmacological treatment
of chronic pain, especially in hospitalized elderly patients, in order to support
them and facilitate their daily life after hospital discharge.
Keywords
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References
- Overview of persistent pain in older adults.Am Psychol. 2014; 69: 197-207
- Pain characteristics of adults 65 years of age and older referred to a tertiary care pain clinic.Pain Res Manag. 2008; 13: 389-394
- Common chronic pain conditions in developed and developing countries: gender and age differences and comorbidity with depression-anxiety disorders.J Pain. 2008; 9: 883-891
- Pain Management in the Elderly Population: a review.Oschner J. 2010; 10: 179-187
- Impact and recognition of cognitive impairment among hospitalized elders.J Hosp Med. 2010; 5: 69-75
- Management of persistent pain in the older patient: a clinical review.JAMA. 2014; 312: 825-836
- Improving the pharmacologic management of pain in older adults: identifying the research gaps and methods to address them.Pain Med. 2011; 12: 1336-1357
- Factors affecting mortality in elderly patients hospitalized for nonmalignant reasons.J Aging Res. 2014; 2014: 584315
- Impact of comorbidity on mortality among older persons with advanced heart failure.J Gen Intern Med. 2012; 27: 513-519
- Guidance on the management of pain in older people.Age Ageing. 2013; 42 (Epub ahead of print)
- An interdisciplinary expert consensus statement on assessment of pain in older persons.Clin J Pain. 2007; 23: S1-S43
- Opioids and the management of chronic severe pain in the elderly: Consensus statement of an international expert panel with focus on the six clinically most often used world health organization step III opioids (Buprenorphine, Fentanyl, Hydromorphone).Met Pain Pract. 2008; 8: 287-313
- The management of persistent pain in older persons.J Am Geriatr Soc. 2002; 50: S205-S224
- Pharmacological Management of Persistent Pain in older persons.J Am Geriatr Soc. 2009; 57: 1331-1346
- Predictors of quality of life among hospitalized geriatric patients with diabetes mellitus upon discharge.Clin Interv Aging. 2016; 11: 1455-1461
- Opioids for chronic pain: new evidence, new strategies, safe prescribing.Am J Med. 2013; 126: S3-S11
- The stigma of low opioid prescription in the hospitalized multimorbid elderly in Italy.Intern Emerg Med. 2015; 10: 305-313
- A close link between opioid-related mortality and medicines commonly used for chronic pain.Pharmacoepidemiol Drug Saf. 2017; 26: 15/16
- Polypharmacy, length of hospital stay, and in-hospital mortality among elderly patients in internal medicine wards. The REPOSI study.Eur J Clin Pharmacol. 2011; 67: 507-519
- Prognostic value of estimated glomerular filtration rate in hospitalized elderly patients.Intern Emerg Med. 2014; 9 ((Epub ahead of print)
- Dementia in elderly persons in a general hospital.Am J Psychiatry. 2000; 157: 704-707
- Mental and behavioral disturbances in dementia: findings from the cache county study on memory in aging.Am J Psychiatry. 2000; 157: 708-714
- The consequences of non-cognitive symptoms of dementia in medical hospital departments.Int J Psychiatry Med. 2003; 33: 257-271
- Dementia and depression in elderly medical inpatients.Int Psychogeriatr. 2000; 12: 67-75
- Chronic back pain is associated with decreased prefrontal and thalamic gray matter density.J Neurosci. 2004; 24: 10410-10415
- Cognitive and emotional control of pain and its disruption in chronic pain.Nat Rev Neurosci. 2013; 14: 502-511
- Cognitive function in patients with chronic pain treated with opioids: characteristics and associated factors.Acta Anaesthesiol Scand. 2012; 56: 1257-1266
- Pain and depression: an integrative review of neurobiological and psychological factors.Curr Psychiatry Rep. 2013; 15 (Epub ahead of print)
- The complex interplay between pain intensity, depression, anxiety and catastrophising with respect to quality of life and disability.Disabil Rehabil. 2009; 31: 1605-1613
- Defining the clinically important difference in pain outcome measures.Pain. 2000; 88: 287-294
- Interpreting the clinical importance of treatment outcomes in chronic pain clinical trials: IMMPACT recommendations.J Pain. 2008; 9: 105-121
Article info
Publication history
Published online: May 28, 2018
Accepted:
May 23,
2018
Received in revised form:
May 10,
2018
Received:
February 16,
2018
Identification
Copyright
© 2018 European Federation of Internal Medicine. Published by Elsevier B.V. All rights reserved.