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Association between ankylosing spondylitis and chronic obstructive pulmonary disease in Taiwan

  • Shih-Wei Lai
    Correspondence
    Corresponding author at: Department of Family Medicine, China Medical University Hospital, No 2, Yu-De Road, Taichung City 404, Taiwan.
    Affiliations
    College of Medicine, China Medical University, Taichung, Taiwan

    Department of Family Medicine, China Medical University Hospital, Taichung, Taiwan
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  • Cheng-Li Lin
    Affiliations
    College of Medicine, China Medical University, Taichung, Taiwan

    Management Office for Health Data, China Medical University Hospital, Taichung, Taiwan
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Published:August 08, 2018DOI:https://doi.org/10.1016/j.ejim.2018.08.006
      One cross-sectional study conducted by Sharif et al. reported that patients with ankylosing spondylitis had a higher proportion of chronic obstructive pulmonary disease than controls (46% versus 18%, P < 0.001) [
      • Sharif K.
      • Watad A.
      • Tiosano S.
      • Yavne Y.
      • Blokh Kerpel A.
      • Comaneshter D.
      • et al.
      The link between COPD and ankylosing spondylitis: a population based study.
      ]. After controlling for age, gender, and smoking status, a significant association exists between ankylosing spondylitis and chronic obstructive pulmonary disease (odds ratio 1.225, P = 0.031) [
      • Sharif K.
      • Watad A.
      • Tiosano S.
      • Yavne Y.
      • Blokh Kerpel A.
      • Comaneshter D.
      • et al.
      The link between COPD and ankylosing spondylitis: a population based study.
      ]. We are interested in these findings. Currently, the relationship between ankylosing spondylitis and chronic obstructive pulmonary disease has not yet been investigated in Taiwan. We designed a cohort analysis to examine the database of the Taiwan National Health Insurance Program with 23 million persons living in an independent country of Taiwan [
      • Ministry of Health and Welfare T
      Taiwan health and welfare report.
      ,
      • Lai S.W.
      • Lin C.L.
      • Liao K.F.
      Population-based cohort study investigating the association between weight loss and pyogenic liver abscesses.
      ]. Subjects aged 20 to 84 years with a new primary diagnosis of ankylosing spondylitis from 2000 to 2012 were selected as the ankylosing spondylitis group based on International Classification of Diseases, Ninth Revision codes (ICD-9 codes 720.0). For every subject with ankylosing spondylitis, 4 sex-matched and age-matched subjects without ankylosing spondylitis were identified as the non-ankylosing spondylitis group. The ankylosing spondylitis group and the non-ankylosing spondylitis group were followed up until a new diagnosis of chronic obstructive pulmonary disease was made (ICD-9 codes 491, 492, 493, and 496) or until the end of 2013.
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      References

        • Sharif K.
        • Watad A.
        • Tiosano S.
        • Yavne Y.
        • Blokh Kerpel A.
        • Comaneshter D.
        • et al.
        The link between COPD and ankylosing spondylitis: a population based study.
        Eur J Intern Med. 2018; 53: 62-65
        • Ministry of Health and Welfare T
        Taiwan health and welfare report.
        ([cited on July 1, 2018, English version])
        • Lai S.W.
        • Lin C.L.
        • Liao K.F.
        Population-based cohort study investigating the association between weight loss and pyogenic liver abscesses.
        Biomed Taiwan. 2017; 7: 38-43
        • Salvi S.
        Tobacco smoking and environmental risk factors for chronic obstructive pulmonary disease.
        Clin Chest Med. 2014; 35: 17-27
        • Chiang Y.Y.
        • Lin H.W.
        Association between psoriasis and chronic obstructive pulmonary disease: a population-based study in Taiwan.
        J Eur Acad Dermatol Venereol. 2012; 26: 59-65
        • Hsu I.L.
        • Lu C.L.
        • Li C.C.
        • Tsai S.H.
        • Chen C.Z.
        • Hu S.C.
        • et al.
        Population-based cohort study suggesting a significantly increased risk of developing chronic obstructive pulmonary disease in people with type 2 diabetes mellitus.
        Diabetes Res Clin Pract. 2018; 138: 66-74