Advertisement

Incidence and impact of new-onset atrial fibrillation on transcatheter mitral valve repair

Published:September 26, 2018DOI:https://doi.org/10.1016/j.ejim.2018.09.014
      Transcatheter mitral valve repair (TMVr) has been approved, in the United States, for the treatment of degenerative mitral valve regurgitation (MR) in certain high surgical risk or inoperable patients. In a recent study by Jabs et al., the in-hospital outcomes (at 12 months) of pre-existing atrial fibrillation (Afib) did not differ considerably from those with sinus rhythm in regard to either major adverse cardiac and cerebrovascular event (MACCE) rates or clinical improvements [
      • Jabs A.
      • von Bardeleben R.S.
      • Boekstegers P.
      • Puls M.
      • Lubos E.
      • Bekeredjian R.
      • et al.
      Effects of atrial fibrillation and heart rate on percutaneous mitral valve repair with mitraclip: results from the TRAnscatheter Mitral valve Interventions (TRAMI) registry.
      ]. However, it should be noted that Afib is a frequently encountered adverse outcome in the TMVr procedure [
      • Jabs A.
      • von Bardeleben R.S.
      • Boekstegers P.
      • Puls M.
      • Lubos E.
      • Bekeredjian R.
      • et al.
      Effects of atrial fibrillation and heart rate on percutaneous mitral valve repair with mitraclip: results from the TRAnscatheter Mitral valve Interventions (TRAMI) registry.
      ] and is, in general, a marker for advanced heart failure [
      • Velu J.F.
      • Kortlandt F.A.
      • Hendriks T.
      • Schurer R.A.J.
      • van Boven A.J.
      • Koch K.T.
      • et al.
      Comparison of outcome after percutaneous mitral valve repair with the mitraclip in patients with versus without atrial fibrillation.
      ]. While previous studies compared the outcomes of pre-existing Afib, there lacks information comparing the outcomes of NOAF in patients with TMVr. Therefore, the objective of this study is to compare in-hospital outcomes in patients with and without NOAF undergoing TMVr.

      Keywords

      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to European Journal of Internal Medicine
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • Jabs A.
        • von Bardeleben R.S.
        • Boekstegers P.
        • Puls M.
        • Lubos E.
        • Bekeredjian R.
        • et al.
        Effects of atrial fibrillation and heart rate on percutaneous mitral valve repair with mitraclip: results from the TRAnscatheter Mitral valve Interventions (TRAMI) registry.
        EuroIntervention. 2017; 12: 1697-1705
        • Velu J.F.
        • Kortlandt F.A.
        • Hendriks T.
        • Schurer R.A.J.
        • van Boven A.J.
        • Koch K.T.
        • et al.
        Comparison of outcome after percutaneous mitral valve repair with the mitraclip in patients with versus without atrial fibrillation.
        Am J Cardiol. 2017; 120: 2035-2040
        • Doshi R.
        • Shlofmitz E.
        • Shah J.
        • Meraj P.
        Comparison of transcatheter mitral valve repair versus surgical mitral valve repair in patients with advanced kidney disease (from the National Inpatient Sample).
        Am J Cardiol. 2017; 121: 762-767
        • Walkey A.J.
        • Wiener R.S.
        • Ghobrial J.M.
        • Curtis L.H.
        • Benjamin E.J.
        Incident stroke and mortality associated with new-onset atrial fibrillation in patients hospitalized with severe sepsis.
        JAMA. 2011; 306: 2248-2254
        • Smilowitz N.R.
        • Gupta N.
        • Ramakrishna H.
        • Guo Y.
        • Berger J.S.
        • Bangalore S.
        Perioperative major adverse cardiovascular and cerebrovascular events associated with noncardiac surgery.
        JAMA Cardiol. 2017; 2: 181-187