- •Clostridium difficile infection incidence achieved a dramatic increase in 2009/2010 in Coimbra, Portugal.
- •Peak incidence coincided with the introduction of alcohol-based hand products.
- •Increase in carbapenem and quinolone prescription had also a potential influence.
- •A possible outbreak of an epidemic strain cannot be excluded.
Abbreviations:CDI (Clostridium difficile infection), CA-CDI (community-associated CDI), HA-CDI (healthcare-associated CDI), OR (odds ratio), LTCF (long-term care facilities)
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- Clinical practice guidelines for clostridium difficile infection in adults and children: 2017 Update by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA).Clin Infect Dis. 2018; 66: 987-994
- Doença associada ao Clostridium difficile–aumento dramático da incidência em doentes internados.Rev Med Interna. 2012; 19: 61-68
- Clostridium difficile infections.in: ECDC Annual epidemiological report for. ECDC, Stockholm2018: 2016
- Clostridium difficile infection in Europe: a hospital-based survey.Lancet. 2011; 377: 63-73
- Clostridium difficile colitis: a retrospective study of incidence and severity before and after institution of an alcohol-based hand rub policy.Am J Infect Control. 2010; 38: 523-528
- Evaluation of the national Cleanyourhands campaign to reduce Staphylococcus aureus bacteraemia and Clostridium difficile infection in hospitals in England and Wales by improved hand hygiene: four year, prospective, ecological, interrupted time series study.BMJ. 2012; 344e3005
- Temporal effects of antibiotic use and hand rub consumption on the incidence of MRSA and Clostridium difficile.J Antimicrob Chemother. 2008; 62: 601-607
- Incidence of Clostridium difficile infections in patients receiving antimicrobial and acid-suppression therapy.Pharmacotherapy. 2011; 31: 642-648
- Identification of risk factors for the development of clostridium difficile-associated diarrhea following treatment of polymicrobial surgical infections.Ann Surg. 2010; 251: 722-727
- Cumulative antibiotic exposures over time and the risk of Clostridium difficile infection.Clin Infect Dis. 2011; 53: 42-48