Differences in left ventricular geometry in hypertensive African-Europeans and Caucasian patients

Published:January 25, 2019DOI:


      • The differences of geometric left ventricular patterns according to race could be curious.
      • The left ventricular remodeling patterns in hypertensive African-Europeans are unknown.
      • Caucasians showed more prevalence of obesity, diabetes and dyslipidaemia.
      • African-Europeans had higher prevalence of concentric remodeling and hypertrophy.
      • These differences could clarify the race differences related to adverse outcomes.



      There are data showing race-related differences regarding left ventricular (LV) geometry in hypertensive patients. Several authors reported that concentric remodeling is the most common remodeling pattern in hypertensive African-Americans, and this pattern may be related to prognosis. There is little information about the LV remodeling patterns in hypertensive Africans that migrated to Europe, which might have different distributions from those seen in African-Americans. The aim our study was to describe the prevalence of LV remodeling patterns in hypertensive African-Europeans and to compare it with that of hypertensive Caucasians.


      This is a descriptive study that included 135 consecutive treated hypertensive African-Europeans and 128 hypertensive Caucasians. Patients were examined by transthoracic echocardiography and categorized into the four classic geometric patterns according to LV mass index (LVMi) and relative wall thickness (RWT).


      The mean age and gender distribution were similar in the 2 groups. Caucasians had significantly higher body mass index, LV diastolic and systolic diameters, while African-Europeans had higher RWT and interventricular septum thickness. No differences in LVMi was found. In the African-European group, the prevalence of normal pattern, concentric remodeling, concentric hypertrophy and eccentric hypertrophy were 13%, 36%, 45% and 6% respectively, while in Caucasians they were 21%, 33%, 34% and 12%, respectively. African-Europeans had a higher prevalence of concentric remodeling and hypertrophy compared to Caucasians (81% vs. 67%, p = .005).


      This study shows important differences in LV geometry between treated African-European and Caucasian hypertensive patients. Also, African-Europeans may have slightly different characteristics compared to African-Americans.


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