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Cardiovascular events and de novo AF following Legionnaires disease

Published:January 24, 2019DOI:https://doi.org/10.1016/j.ejim.2019.01.010
      Cardiovascular (CV) diseases are a worldwide major cause of death. This fact relates to a number of risk factors [
      • Clayton T.C.
      • Thompson M.
      • Meade T.W.
      Recent respiratory infection and risk of cardiovascular disease: case-control study through a general practice database.
      ], but infection might be pointed as one of utmost importance as it triggers inflammation, thrombosis and endothelial dysfunction, leading to atherosclerosis. This is true not only in the acute phase of the infection, but also in the following years. Low respiratory tract infections, specially if severe, have been associated with CV events [
      • Bergh C.
      • Fall K.
      • Udumyan R.
      • Sjöqvist H.
      • Fröbert O.
      • Montgomery S.
      Severe infections and subsequent delayed cardiovascular disease.
      ].
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