Recommending marijuana use: Violation of the Hippocratic aphorism of “do good or do no harm”

Published:January 24, 2019DOI:


      • Legalization of cannabis is spreading around the globe without having secured its safety.
      • Cannabis use has been charged with mental, cardiovascular and other health problems.
      • It constitutes a public health hazard with alarming preponderance in younger age groups.
      • Recommending marijuana use violates the Hippocratic aphorism of “Do Good or Do No Harm”.
      • The evidence-based medicine paradigm should be applied to the field of medical cannabis.
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        • Manolis T.A.
        • Manolis A.A.
        • Manolis A.S.
        Cannabis associated “high” cardiovascular morbidity and mortality: marijuana smoke like tobacco smoke? A Déjà Vu/Déjà Vécu Story?.
        Mini Rev Med Chem. 2018 Nov 13; ([Epub ahead of print])
        • Hauser W.
        • Finn D.P.
        • Kalso E.
        • et al.
        European Pain Federation (EFIC) position paper on appropriate use of cannabis-based medicines and medical cannabis for chronic pain management.
        Eur J Pain. 2018; 22: 1547-1564
        • Barnes M.P.
        The case for medical cannabis-an essay by M P Barnes.
        BMJ. 2018; 362k3230
        • Rezkalla S.
        • Kloner R.A.
        Cardiovascular effects of marijuana.
        Trends Cardiovasc Med. 2018 Nov 10; ([pii: S1050-1738(18)30141-5]. [Epub ahead of print])
        • Kalla A.
        • Krishnamoorthy P.M.
        • Gopalakrishnan A.
        • Figueredo V.M.
        Cannabis use predicts risks of heart failure and cerebrovascular accidents: results from the National Inpatient Sample.
        J Cardiovasc Med (Hagerstown). 2018; 19: 480-484
        • Desai R.
        • Patel U.
        • Deshmukh A.
        • Sachdeva R.
        • Kumar G.
        Burden of arrhythmia in recreational marijuana users.
        Int J Cardiol. 2018; 264: 91-92
        • Callaghan R.C.
        • Allebeck P.
        • Sidorchuk A.
        Marijuana use and risk of lung cancer: a 40-year cohort study.
        Cancer Causes Control. 2013; 24: 1811-1820
        • Kilmer B.
        Recreational cannabis - minimizing the health risks from legalization.
        N Engl J Med. 2017; 376: 705-707
        • Abouk R.
        • Adams S.
        Examining the relationship between medical cannabis laws and cardiovascular deaths in the US.
        Int J Drug Policy. 2018; 53: 1-7
        • Shen J.J.
        • Shan G.
        • Kim P.C.
        • et al.
        Trends and related factors of cannabis-associated emergency department visits in the United States: 2006–2014.
        J Addict Med. 2018 Nov 9; ([Epub ahead of print])
        • Kaufman T.M.
        • Fazio S.
        • Shapiro M.D.
        Brief commentary: marijuana and cardiovascular disease-what should we tell patients?.
        Ann Intern Med. 2019 Jan 8; ([Epub ahead of print])