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Raynaud's phenomenon and inflammatory bowel disease: The possible role of microcirculation

  • Vera R. Bernardino
    Correspondence
    Corresponding author at: Serviço Medicina Interna 7.2, Hospital Curry Cabral, Rua da Beneficência 8, 1069-166 Lisboa, Portugal.
    Affiliations
    Unidade de Doenças Auto-Imunes, Internal Medicine Department 7.2, Hospital Curry Cabral, Centro Hospitalar Universitário Lisboa Central, Lisboa, Portugal
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  • Ana Catarina Rodrigues
    Affiliations
    Unidade de Doenças Auto-Imunes, Internal Medicine Department 7.2, Hospital Curry Cabral, Centro Hospitalar Universitário Lisboa Central, Lisboa, Portugal
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  • António Panarra
    Affiliations
    Unidade de Doenças Auto-Imunes, Internal Medicine Department 7.2, Hospital Curry Cabral, Centro Hospitalar Universitário Lisboa Central, Lisboa, Portugal
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Published:February 06, 2019DOI:https://doi.org/10.1016/j.ejim.2019.02.001
      Vascular pathology is increasingly more recognized as an extra-intestinal manifestation of Inflammatory Bowel Disease (IBD) [
      • Koutroubakis I.E.
      • Sfiridaki A.
      • Tsiolakidou G.
      • et al.
      Genetic risk factors in patients with inflammatory bowel disease and vascular complications: case-control study.
      ,
      • Tan V.
      • Chung A.
      • Yan B.P.
      • et al.
      Venous and arterial disease in inflammatory bowel disease.
      ]. Raynaud's phenomenon (RP), a syndrome characterized by recurrent episodes of digital artery vasospasm, may be secondary to systemic diseases and is rarely associated with IBD [
      • Prete M.
      • Fatone M.C.
      • Favoino E.
      • et al.
      Raynaud's phenomenon: from molecular pathogenesis to therapy.
      ,
      • Karmiris K.
      • Avgerinos A.
      • Tavernakari A.
      • et al.
      Prevalence and characteristics of extra-intestinal manifestations in a large cohort of greek patients with inflammatory bowel disease.
      ]. RP occurs in the presence of abnormalities of dermal capillaries, the morphology of which can be examined by nailfold capillaroscopy (NFC), a standardized non-invasive technique [
      • Cutolo M.
      • Sulli A.
      • Smith V.
      How to perform and interpret capillaroscopy.
      ].

      Keywords

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      References

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        Genetic risk factors in patients with inflammatory bowel disease and vascular complications: case-control study.
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