Highlights
- •A national sample was employed.
- •We evaluated secular trends in the association between obesity and hypertension.
- •The magnitude of this association has been increasing over time.
Abstract
Objective
To examine the secular trends in the association between obesity and hypertension
among American adults between 1999 and 2014.
Methods
Data from the 1999–2014 National Health and Nutrition Examination Survey (eight survey
cycles) were used. Obesity was determined from measured body mass index, with hypertension
assessed from measured blood pressure and self-reported medication use. Meta-regression
was used to examine the linear, quadratic, and cubic trends of the relationship between
the observed odds ratio effect sizes (obesity and hypertension) and the NHANES cycles
(year) using a random-effects model.
Results
Across the years of 1999 to 2014, there was a significant, positive linear trend (p = .006) in the association between overweight/obesity and hypertension.
Conclusion
Our findings suggest that the association between overweight/obesity and hypertension
is becoming stronger over time. Continued surveillance of temporal changes associated
with obesity and hypertension is necessary to monitor how such changes may underlie
changes in the risk for chronic disease.
Significance of the Study
This novel study evaluates whether the magnitude of association between obesity and
hypertension has changed over the last 15-years.
Keywords
Abbreviations:
BMI (Body Mass Index), BP (Blood Pressure), NHANES (National Health and Nutrition Examination Survey)To read this article in full you will need to make a payment
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References
- Overweight, obesity, and mortality from cancer in a prospectively studied cohort of US adults.N Engl J Med. 2003; 348: 1625-1638
- Body-mass index and mortality in a prospective cohort of US adults.N Engl J Med. 1999; 341: 1097-1105
- Race and obesity in adolescent hypertension.. 2017; 139(5)e20161433
- Overweight and hypertension: a review.Circulation. 1969; 39: 403-421
- The effects of hypertension and obesity on total health-care expenditures of diabetes patients in the United States.Appl Econ Lett. 2013; 20: 649-652
- Insulin resistance: a multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia, and atherosclerotic cardiovascular disease.Diabetes Care. 1991; 14: 173-194
- Prevalence of obesity and trends in the distribution of body mass index among US adults, 1999–2010.Jama. 2012; 307: 491-497
- Prevalence and trends in obesity among US adults, 1999-2008.Jama. 2010; 303: 235-241
- Hypertension prevalence and control among adults: United States, 2015–2016.in: NCHS Data Brief. vol. 289. 2017: 1-8
- Isolated systolic hypertension and mortality after age 60 years: a prospective population-based study.Am J Epidemiol. 1983; 118: 365-376
- The relative contributions of different levels of overweight and obesity to the increased prevalence of diabetes in the United States: 1976–2004.Prev Med. 2007; 45: 348-352
- Trends in prevalence, awareness, management, and control of hypertension among United States adults, 1999 to 2010.J Am Coll Cardiol. 2012; 60: 599-606
- Trends in obesity and severe obesity prevalence in US youth and adults by sex and age, 2007-2008 to 2015-2016.JAMA. 2018; 319: 1723-1725https://doi.org/10.1001/jama.2018.3060
- The kidney, hypertension, and obesity.hypertension. 2003; 41: 625-633
- Obesity-induced hypertension. Renal function and systemic hemodynamics.Hypertension. 1993; 22: 292-299
- Mechanisms of obesity-associated cardiovascular and renal disease.Am J Med Sci. 2002; 324: 127-137
- Progression of chronic kidney disease: the role of blood pressure control, proteinuria, and angiotensin-converting enzyme inhibition: a patient-level meta-analysis.Ann Intern Med. 2003; 139: 244-252
- Systolic blood pressure, arterial rigidity, and risk of stroke.Jama. 1981; 245: 1225-1229
- Obesity and the risk of heart failure.N Engl J Med. 2002; 347: 305-313
- Obesity: impact on cardiovascular disease.Circulation. 1998; 98: 1472-1476
- Hypertension in obesity.Med Clin. 2011; 95: 903-917
- Obesity and cardiovascular disease: risk factor, paradox, and impact of weight loss.J Am Coll Cardiol. 2009; 53: 1925-1932
- Temporal trends in BMI among adults with diabetes.Diabetes Care. 2001; 24: 1584-1589
- Obesity-induced hypertension: new concepts from the emerging biology of obesity.hypertension. 1999; 33: 537-541
- Weight gain–induced blood pressure elevation.hypertension. 2000; 35: 1135-1140
- Potential US population impact of the 2017 ACC/AHA high blood pressure guideline.Circulation. 2018; 137: 109-118
- Prevalence of Obesity among Adults and Youth: United States, 2011–2014.US Department of Health and Human Services, Centers for Disease Control and Prevention, National Center for Health Statistics, 2015
- National Health and nutrition examination survey 1999–2000: effect of observer training and protocol standardization on reducing blood pressure measurement error.J Clin Epidemiol. 2003; 56: 768-774
- Change in weight status and development of hypertension.vol. 137. 2016: e20151662 (3)
- Recent weight gain in patients with newly diagnosed obstructive sleep apnea.J Hypertens. 1999; 17: 1297-1300
- Trends in hypertension.Indian Heart J. 2012; 64: 132-133https://doi.org/10.1016/S0019-4832(12)60046-7
- Body-mass index and incidence of cancer: a systematic review and meta-analysis of prospective observational studies.Lancet. 2008; 371: 569-578
- Slightly increased BMI at Young Age is a Risk Factor for Future Hypertension in Japanese Men.13. 2018: e0191170 (1)
- Hypertension Prevalence and Control among Adults: United States, 2011–2014.US Department of Health and Human Services, Centers for Disease Control and Prevention, National Center for Health Statistics, 2015
Article info
Publication history
Published online: March 01, 2019
Accepted:
February 20,
2019
Received in revised form:
January 23,
2019
Received:
November 5,
2018
Identification
Copyright
© 2019 European Federation of Internal Medicine. Published by Elsevier B.V. All rights reserved.