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Cardiovascular comorbidities in patients with West Nile disease infection: An unexplored issue

  • Author Footnotes
    1 The authors equally contribute to the manuscript.
    Loris Roncon
    Correspondence
    Corresponding author at: Department of Cardiology, Santa Maria della Misericordia Hospital, Via Tre Martiri 140, 45100 Rovigo, Italy.
    Footnotes
    1 The authors equally contribute to the manuscript.
    Affiliations
    Department of Cardiology, Santa Maria della Misericordia Hospital, Rovigo, Italy
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  • Author Footnotes
    1 The authors equally contribute to the manuscript.
    Marco Zuin
    Footnotes
    1 The authors equally contribute to the manuscript.
    Affiliations
    Section of Internal and Cardiopulmonary Medicine, University of Ferrara, Faculty of Medicine, Ferrara, Italy
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  • Author Footnotes
    1 The authors equally contribute to the manuscript.
    Filippo Viviani
    Footnotes
    1 The authors equally contribute to the manuscript.
    Affiliations
    Division of Infectious Disease, Santa Maria della Misericordia Hospital, Rovigo, Italy
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  • Author Footnotes
    1 The authors equally contribute to the manuscript.
Published:March 20, 2019DOI:https://doi.org/10.1016/j.ejim.2019.03.011
      Over the latest years, the incidence of West-Nile virus (WNV) infection has increased dramatically in some Italian regions, as in the North-east of Italy [
      • Barzon L.
      • Pacenti M.
      • Franchin E.
      • Squarzon L.
      • Lavezzo E.
      • Toppo S.
      • et al.
      Novel West Nile virus lineage 1a full genome sequences from human cases of infection in North-Eastern Italy, 2011.
      ,
      • Monaco F.
      • Savini G.
      • Calistri P.
      • Polci A.
      • Pinoni C.
      • Bruno R.
      • et al.
      2009 West Nile disease epidemic in Italy: first evidence of overwintering in Western Europe?.
      ]. However, data regarding the prevalence of cardiovascular (CV) comorbidities and their potential impact on the short-term outcome of these patients have never been investigated. Generally, preexisting chronic conditions such as CV (CVD), metabolic and respiratory diseases are often associated with a greater risk of progression to a worst outcome. Aim of the present study is to assess the prevalence of CV comorbidities and their potential effect on the short-term survival in patients with confirmed WNV infection.

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