Systemic lupus erythematosus (SLE) is a heterogeneous autoimmune condition characterized
by a wide range of cytokines and antibodies production. The interleukin 10 (IL-10)
is one of the most studied cytokines, with pleiomorphic functions, also involved in
lymphocytes cell growth and differentiation. Most studies identified higher IL-10
levels in lupus patients when compared to control subjects and also significant correlations
of serum IL-10 with lupus disease activity and anti-DNA titers (revised by Peng et
al) [
[1]
]. However, treatments targeting interleukins have failed to be successful in lupus
patients, therefore there is need to identify the relation of certain cytokines with
particular lupus organ impairments [[2]
].Keywords
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Article info
Publication history
Published online: April 26, 2019
Accepted:
April 22,
2019
Received in revised form:
January 16,
2019
Received:
October 25,
2018
Identification
Copyright
© 2019 European Federation of Internal Medicine. Published by Elsevier B.V. All rights reserved.
