Advertisement

Infective endocarditis in patients with cardiac implantable electronic devices: Impact of comorbidities on outcome

      We read with interest the paper by Armiñanzasa et al., recently published in the European Journal of Internal Medicine [
      • Arminanzas C.
      • Farinas-Alvarez C.
      • Zarauza J.
      • Munoz P.
      • Gonzalez Ramallo V.
      • Martinez Selles M.
      • et al.
      Role of age and comorbidities in mortality of patients with infective endocarditis.
      ]. The authors provided an important analysis of a large, prospectively collected, cohort of patients with possible/definite infective endocarditis enrolled in the Spanish Collaboration on Endocarditis—Grupo de Apoyo al Manejo de la Endocarditis infecciosa en España (GAMES) registry maintained by 39 Spanish hospitals from January 2008 to April 2015. According to this analysis an age ≥ 80 years, a Charlson Comorbidity Index score ≥ 3, and absence of surgical reparation, were independent predictors of mortality. Consequently, the authors suggest to carefully consider these parameters in each patient at the time of multidisciplinary evaluations targeted to a proper assessment of the patient-specific risk/benefit ratio of interventions directed to treat infective endocarditis.
      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to European Journal of Internal Medicine
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • Arminanzas C.
        • Farinas-Alvarez C.
        • Zarauza J.
        • Munoz P.
        • Gonzalez Ramallo V.
        • Martinez Selles M.
        • et al.
        Role of age and comorbidities in mortality of patients with infective endocarditis.
        Eur J Intern Med. 2019; 64 (Epub 2019 Mar 21): 63-71https://doi.org/10.1016/j.ejim.2019.03.006
        • Diemberger I.
        • Parisi Q.
        • De Filippo P.
        • Narducci M.L.
        • Zanon F.
        • Potenza D.R.
        • et al.
        Detect long-term complications after ICD replacement (DECODE): rationale and study design of a multicenter Italian registry.
        Clin Cardiol. 2015; 38: 577-584
        • Diemberger I.
        • Biffi M.
        • Martignani C.
        • Boriani G.
        From lead management to implanted patient management: indications to lead extraction in pacemaker and cardioverter-defibrillator systems.
        Expert Rev Med Devices. 2011; 8: 235-255
        • Habib G.
        • Lancellotti P.
        • Antunes M.J.
        • Bongiorni M.G.
        • Casalta J.P.
        • Del Zotti F.
        • et al.
        ESC Guidelines for the management of infective endocarditis: the task force for the management of infective endocarditis of the European Society of Cardiology (ESC). Endorsed by: European Association for Cardio-Thoracic Surgery (EACTS), the European Association of Nuclear Medicine (EANM).
        Eur Heart J. 2015; 2015: 3075-3128
        • Kusumoto F.M.
        • Schoenfeld M.H.
        • Wilkoff B.L.
        • Berul C.I.
        • Birgersdotter-Green U.M.
        • Carrillo R.
        • et al.
        HRS expert consensus statement on cardiovascular implantable electronic device lead management and extraction. Heart rhythm.
        2017. 2017; 14: e503-e551
        • Diemberger I.
        • Migliore F.
        • Biffi M.
        • Cipriani A.
        • Bertaglia E.
        • Lorenzetti S.
        • et al.
        The "subtle" connection between development of cardiac implantable electrical device infection and survival after complete system removal: an observational prospective multicenter study.
        Int J Cardiol. 2018; 250: 146-149
        • Diemberger I.
        • Biffi M.
        • Lorenzetti S.
        • Martignani C.
        • Raffaelli E.
        • Ziacchi M.
        • et al.
        Predictors of long-term survival free from relapses after extraction of infected CIED.
        Europace. 2018; 20: 1018-1027
        • Habib A.
        • Le K.Y.
        • Baddour L.M.
        • Friedman P.A.
        • Hayes D.L.
        • Lohse C.M.
        • et al.
        Predictors of mortality in patients with cardiovascular implantable electronic device infections.
        Am J Cardiol. 2013; 111: 874-879
        • Shariff N.
        • Eby E.
        • Adelstein E.
        • Jain S.
        • Shalaby A.
        • Saba S.
        • et al.
        Health and economic outcomes associated with use of an antimicrobial envelope as a standard of Care for Cardiac Implantable Electronic Device Implantation.
        J Cardiovasc Electrophysiol. 2015; 26: 783-789
        • Vicent L.
        • Saldivar H.G.
        • Bouza E.
        • Munoz P.
        • Cuerpo G.
        • de Alarcon A.
        • et al.
        Prognostic implications of a negative echocardiography in patients with infective endocarditis.
        Eur J Intern Med. 2018; 52: 40-48
        • Garcia-Granja P.E.
        • Lopez J.
        • Vilacosta I.
        • Sarria C.
        • Ladron R.
        • Olmos C.
        • et al.
        Surgery changes prognosis in infective endocarditis: the importance of post-surgical clinical evolution.
        Eur J Intern Med. 2018; 55: 52-56
        • Diemberger I.
        • Bonfiglioli R.
        • Martignani C.
        • Graziosi M.
        • Biffi M.
        • Lorenzetti S.
        • et al.
        Contribution of PET imaging to mortality risk stratification in candidates to lead extraction for pacemaker or defibrillator infection: a prospective single center study.
        Eur J Nucl Med Mol Imaging. 2019; 46: 194-205

      Linked Article