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Corresponding author at: Department of Dermatology, Venereology and Leprology, Postgraduate Institute of Medical Education and Research, Sector 12, Chandigarh 160012, India.
An elderly man sought dermatology consultation for gradually progressive, mildly itchy,
photosensitive rash on dorsum of hands for a month. Apart from the skin lesions, he
also complained of intermittent diarrhoea which he attributed to his underlying Crohn's
disease. He additionally had difficulty in recalling recent events for last few months.
On examination (Fig. 1), well demarcated erythematous to dusky edematous plaques were noted symmetrically
on dorsal aspect of hands and fingers. Skin of no other part was involved. Lesional
skin biopsy demonstrated epidermal spongiosis, elongation of rete ridges, hyaline
degeneration of collagen and mild perivascular lymphocytic infiltrate in dermis. What
is your diagnosis?
Fig. 1a: Well demarcated erythematous to dusky edematous plaques distributed symmetrically
on dorsal aspect of hands and fingers. b: Complete clearance of lesions at 12 weeks
after niacin supplementation