Antiphospholipid antibodies (aPL) are frequently detected in immune thrombocytopenia
(ITP) and whether they play a role in ITP prognosis is controversial. Previous studies
have shown that aPL positivity may not be associated with either platelet counts or
response to treatment [
1
,
2
,
3
,
- Comellas-Kirkerup L.
- Hernandez-Molina G.
- Cabral A.R.
Antiphospholipid-associated thrombocytopenia or autoimmune hemolytic anemia in patients
with or without definite primary antiphospholipid syndrome according to the Sapporo
revised classification criteria: a 6-year follow-up study.
Blood. 2010; 116: 3058-3063
4
]; however, heterogeneity in the classification of ITP outcomes and high variability
of aPL assays performed across studies may affect results consistency.Keywords
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References
- Relevance of antiphospholipid antibody profile in the clinical outcome of ITP: a single-centre study.Hematology. 2019; 24: 134-138
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- Antiphospholipid antibodies in adults with immune thrombocytopenic purpura.Br J Haematol. 2008; 142: 638-643
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Article info
Publication history
Published online: August 22, 2019
Accepted:
August 17,
2019
Received in revised form:
August 14,
2019
Received:
May 29,
2019
Identification
Copyright
© 2019 European Federation of Internal Medicine. Published by Elsevier B.V. All rights reserved.
